Anne M Strohecker, PhD
College of Medicine
Cancer Biology and Genetics
Molecular Biology and Cancer Genetics
Dr. Strohecker is interested in understanding how autophagy, a program that regulates protein and organelle quality control, impacts tumorigenesis. Her projects focus on (i) the identification of novel autophagy regulators and their functional relevance for lung tumorigenesis, and (ii) the role of autophagy in the biology of a subset of aggressive sarcomas, the malignant peripheral nerve sheath tumors (MPNSTs). Dr. Strohecker’s lab uses a combination of genetically engineered mouse models, microscopy, and loss of function screening as tools to answer these questions. These experiments will enhance the understanding of autophagy and have the potential to uncover new therapeutic targets for cancer.