Carlos Castro, PhD
College of Engineering
Mechanical & Aerospace Engineering
Carcinoma, Intraductal, Noninfiltrating, Down Syndrome, Rupture, Cancer
Carlos Castro, PhD, brings an engineering perspective as a member of the Leukemia Research Program at the OSUCCC – James.He seeks to use engineering approaches with nanotechnology and biophysics experimental tools to characterize and model physical properties and behaviors of complex biological systems. His goals are to create an array of functional DNA nanotechnology-based tools for measurement, manipulation and delivery applications in biological systems. Results from one of his recent studies indicated that DNA origami nanostructures can circumvent efflux-pump-mediated drug resistance in leukemia cells at clinically relevant drug concentrations. Dr. Castro has co-authored numerous articles appearing in well-respected journals such as ACS Nano, Proceedings of the National Academy of Sciences, and Advanced Materials.