David M Lucas, PhD

David Lucas


College of Medicine


Internal Medicine

Academic Title

Res Asst Professor

Research Program

Leukemia Research

Research Interest

>Leukemia, Lymphocytic, Chronic, B-Cell ● Cancer ● Leukemia ● Lymphoma, Mantle-Cell ● Precursor Cell Lymphoblastic Leukemia-Lymphoma ● Leukemia, Myeloid, Acute ● Leukemia, Hairy Cell ● Lymphoma ● Leukemia, B-Cell ● Neutropenia

David Lucas, PhD, is a member of the Leukemia Research Program at the OSUCCC – James, where his work focuses on the pharmacology of novel anti-leukemic agents and on the role of transcriptional and translational regulation in tumor cell survival and drug resistance.

Among his recent research projects is the generation and characterization of a mouse model with BRAF-mutated B-cell leukemia. The BRAF mutation, common in some types of solid tumors, is relatively uncommon in B-cell cancers and thus its impact on disease development and progression has not been well studied.

Dr. Lucas has co-authored more than 125 articles that have appeared in well-respected publications, including Blood, Blood Advances, Journal of Hematology & Oncology and PLoS One.

Dr. Lucas is also the director of the OSUCCC – James Leukemia Tissue Bank, which provides high-quality samples from patients with all types of hematologic malignancies to investigators who study the biology, genetics and treatment of blood cancers.


  • BA, Miami University

    Oxford, OH (USA)

  • Fellowship, Fred Hutchinson Cancer Research Center

    Seattle, WA (USA)


  • Postdoctoral Fellowship

    Fred Hutchinson Cancer Research Center

    Seattle, WA (USA)

Office Location

A350B Starling Loving

320 W 12th Ave, Columbus, OH 43210



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