Dawn S Chandler, PhD

Dawn Chandler

College

College of Medicine

Department/Division

Pediatrics

Academic Title

Assoc Professor

Research Program

Molecular Biology and Cancer Genetics

Research Interest

Cancer, Muscular Atrophy, Spinal, Rhabdomyosarcoma, DNA Damage, Breast Cancer, Loss of Heterozygosity, Anoxia, Carcinoma, Renal Cell, von Hippel-Lindau Disease, Myopathies, Structural, Congenital

Dawn Chandler, PhD, is a member of the Molecular Biology and Cancer Genetics Program at the OSUCCC – James, where her work focuses on the regulation of pre-mRNA splicing and how its disruption can lead to pediatric diseases such as cancer.

In one recent study, her team’s research identified for the first time a clear mechanism for regulating damage-induced oncogene MDM2 splicing. The work offers potential strategies for manipulating MDM2 expression via splicing modulation.

Dr. Chandler has co-authored numerous articles in well-respected publications, including Human Molecular Genetics, Nucleic Acids Research and the Journal of Biological Chemistry.


Education and Background

Office Location

WA5023 Columbus Children's Research Institute

700 Children's Drive, Columbus, OH 43205


614-722-5302

614-722-5895



Publications

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