Deliang Guo, PhD
College of Medicine
Glioblastoma, Brain Cancer, Cancer, Melanoma, Glioma, Hypertension
Dr. Guo's lab's long term goal is to determine the key molecular targets in cancer metabolism and translate it to clinic. The lab's detailed research interests are to: 1) Investigate the molecular link between oncogenic signaling PI3K/Akt and Ras/MEK/ERK signaling with cancer metabolism. 2) Develop the strategy via targeting SREBP-1 to treat cancer. 3) Dissect cholesterol metabolism and its intersection with oncogenic signaling. 4) Delineate the relationship between autophagy and cancer metabolism, and determine the metabolomics profile in cancer. 5) Define lipid droplet role and its dynamic regulation in cancer and reveal its relationship with autophagy and cancer metabolism.