Denis C Guttridge, PhD

Denis Guttridge

Associate Director for Basic Research
OSU Comprehensive Cancer Center

Director of Research and Management for Cancer Cachexia

Professor, Department of Cancer Biology & Genetics


College of Medicine

Academic Title


Research Program

Molecular Carcinogenesis and Chemoprevention

Research Interest

Cancer, Cachexia, Inflammation, Muscular Dystrophy, Duchenne, Head and Neck Cancer, Muscular Dystrophies, Rhabdomyosarcoma, Weight Loss, Liposarcoma

Dr. Guttridge's laboratory studies the NF-kB family of transcription factors and the role they play in cell growth and differentiation. The long-term goal is not only to better dissect the function and mechanisms by which NF-kB regulates muscle differentiation and turnover associated with muscle disorders, but also to translate this information into a better understanding of the role of NF-kB in tumor development.

Education and Background

Office Location

910 Biomedical Research Tower

460 W 12th Ave, Columbus, OH 43210




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