Gina Sizemore, PhD
College of Medicine
Molecular Biology and Cancer Genetics
Research in the Sizemore lab integrates in vitro and in vivo modeling of the brain metastatic tumor microenvironment (TME) to provide mechanistic insight into how the brain metastatic TME contributes to breast cancer metastatic progression. Current studies aim to elucidate whether platelet derived growth factor receptor-beta (PDGFRß) signaling is a promising pathway for diagnostic and/or therapeutic purposes for metastatic breast cancer patients.