Ioanna Papandreou, PhD

Ioanna Papandreou


College of Medicine


Radiation Oncology

Academic Title

Asst Professor

Research Program

Molecular Biology and Cancer Genetics

Research Interest

Cancer, Anoxia, Endoplasmic Reticulum Stress, Oxidative stress, Multiple Myeloma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Acidosis, Adenomatous Polyposis Coli, Cancer, Vascular Tissue

The dysfunctional tumor vasculature and the deregulated cancer cell proliferation create areas of oxygen- and nutrient- deprivation in solid tumors. Cells within the tumor respond to these microenvironmental stresses by activating adaptive mechanisms that allow malignant progression under such harsh conditions. Dr. Papandreou is investigating stress-modulated transcriptional and biochemical pathways, with particular emphasis given to the reprogramming of glucose and lipid metabolism under hypoxic environments. Her research employs in vitro models of hypoxia and hypoglycemia, tumor xenotransplantation protocols and genetically engineered mouse models with the goal to identify new targets for therapeutic development.

Office Location

324 Tzagournis Med Res Facility

420 W 12th Ave, Columbus, OH 43210


Back to Researcher Search

Please enter a keyword (i.e. Name, Research Interest) or choose a Research Program


Please enter a keyword (i.e. Name, Cancer Type) or choose a Principle Investigator


Search for Clinical Trials

Find a Scientific Publication