Jeffrey J Chalmers, PhD

College

College of Engineering

Department/Division

Chemical & Biomolecular Engineering

Academic Title

Professor

Research Program

Translational Therapeutics

Research Interest

Cancer, Coronary Disease, Rupture, Alzheimer Disease, Carcinoma, Squamous Cell, Breast Cancer

The research in Dr. Chalmer's labs involves the development of fundamental understanding and applications of the interaction of hydrodynamic and magnetic forces and cells. This work can range from the development of fundamental mathematical relationships describing physical phenomena to the development of simple, robust instruments for use in a clinical setting.

Education and Background

Office Location

333B Koffolt Laboratories

140 W 19th Avenue, Columbus, Ohio 43210

614-292-2727

614-292-3769

chalmers.1@osu.edu

Publications

Mechanotransduction Effects on Endothelial Cell Proliferation via CD31 and VEGFR2: Implications for Immunomagnetic Separation.

Mahajan KD, Nabar GM, Xue W, Anghelina M, Moldovan N, Chalmers J, Winter J

Biotechnol J in press 07/21/2017
Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells.

Zhu X, Badawi M, Pomeroy S, Sutaria DS, Xie Z, Baek A, Jiang J, Elgamal OA, Mo X, Perle K, Chalmers J, Schmittgen TD, Phelps MA

J Extracell Vesicles 6 1324730 01/01/2017
Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery.

Sutaria DS, Jiang J, Elgamal OA, Pomeroy SM, Badawi M, Zhu X, Pavlovicz R, Azevedo-Pouly ACP, Chalmers J, Li C, Phelps MA, Schmittgen TD

J Extracell Vesicles 6 1333882 01/01/2017
Multispectral Imaging Analysis of Circulating Tumor Cells in Negatively Enriched Peripheral Blood Samples.

Miller B, Lustberg M, Summers TA, Chalmers JJ

Methods Mol Biol 1634 219-234 01/01/2017
Effect of surgical intervention on circulating tumor cells in patients with squamous cell carcinoma of the head and neck using a negative enrichment technology.

Jatana KR, Balasubramanian P, McMullen KP, Lang JC, Teknos TN, Chalmers JJ

Head Neck 38 1799-1803 12/01/2016
Multiparameter Evaluation of the Heterogeneity of Circulating Tumor Cells Using Integrated RNA In Situ Hybridization and Immunocytochemical Analysis.

Wu Y, Park KJ, Deighan C, Amaya P, Miller B, Pan Q, Zborowski M, Lustberg M, Chalmers J

Front Oncol 6 234 01/01/2016
Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells.

Oliveira-Costa JP, de Carvalho AF, daSilveira GG, Amaya P, Wu Y, Park KJ, Gigliola MP, Lustberg M, Cavicchioli Buim ME, Ferreira EN, Kowalski LP, Chalmers JJ, Soares FA, Carraro DM, Ribeiro-Silva A, Oliveira-Costa JP, Carvalho AF, Silveira GG, Amaya P, Wu Y, Park KJ, Gigliola MP, Lustberg M, Buim ME, Ferreira EN, Kowalski LP, Chalmers JJ, Soares FA, Carraro DM, Ribeiro-Silva A, Oliveira-Costa JP, de Carvalho AF, da Silveira da GG, Amaya P, Wu Y, Park KJ, Gigliola MP, Lustberg M, Buim ME, Ferreira EN, Kowalski LP, Chalmers JJ, Soares FA, Carraro DM, Ribeiro-Silva A

Oncotarget 6 20902-20 08/28/2015
Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells.

Oliveira-Costa JP, de Carvalho AF, daSilveira GG, Amaya P, Wu Y, Park KJ, Gigliola MP, Lustberg M, Cavicchioli Buim ME, Ferreira EN, Kowalski LP, Chalmers JJ, Soares FA, Carraro DM, Ribeiro-Silva A, Oliveira-Costa JP, Carvalho AF, Silveira GG, Amaya P, Wu Y, Park KJ, Gigliola MP, Lustberg M, Buim ME, Ferreira EN, Kowalski LP, Chalmers JJ, Soares FA, Carraro DM, Ribeiro-Silva A, Oliveira-Costa JP, de Carvalho AF, da Silveira da GG, Amaya P, Wu Y, Park KJ, Gigliola MP, Lustberg M, Buim ME, Ferreira EN, Kowalski LP, Chalmers JJ, Soares FA, Carraro DM, Ribeiro-Silva A

Oncotarget 6 20902-20 08/28/2015
Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells.

Oliveira-Costa JP, de Carvalho AF, daSilveira GG, Amaya P, Wu Y, Park KJ, Gigliola MP, Lustberg M, Cavicchioli Buim ME, Ferreira EN, Kowalski LP, Chalmers JJ, Soares FA, Carraro DM, Ribeiro-Silva A, Oliveira-Costa JP, Carvalho AF, Silveira GG, Amaya P, Wu Y, Park KJ, Gigliola MP, Lustberg M, Buim ME, Ferreira EN, Kowalski LP, Chalmers JJ, Soares FA, Carraro DM, Ribeiro-Silva A, Oliveira-Costa JP, de Carvalho AF, da Silveira da GG, Amaya P, Wu Y, Park KJ, Gigliola MP, Lustberg M, Buim ME, Ferreira EN, Kowalski LP, Chalmers JJ, Soares FA, Carraro DM, Ribeiro-Silva A

Oncotarget 6 20902-20 08/28/2015
CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.

Mathsyaraja H, Thies K, Taffany DA, Deighan C, Liu T, Yu L, Fernandez SA, Shapiro C, Otero J, Timmers C, Lustberg MB, Chalmers J, Leone G, Ostrowski MC

Oncogene 34 3651-61 07/01/2015
Tailoring the surface charge of dextran-based polymer coated SPIONs for modulated stem cell uptake and MRI contrast.

Barrow M, Taylor A, Nieves DJ, Bogart LK, Mandal P, Collins CM, Moore LR, Chalmers JJ, Lévy R, Williams SR, Murray P, Rosseinsky MJ, Adams DJ

Biomater Sci 3 608-16 04/01/2015
Feasibility study of red blood cell debulking by magnetic field-flow fractionation with step-programmed flow.

Moore LR, Williams PS, Nehl F, Abe K, Chalmers JJ, Zborowski M

Anal Bioanal Chem 406 1661-70 02/01/2014
Heterogeneous atypical cell populations are present in blood of metastatic breast cancer patients.

Lustberg MB, Balasubramanian P, Miller B, Garcia-Villa A, Deighan C, Wu Y, Carothers S, Berger M, Ramaswamy B, Macrae ER, Wesolowski R, Layman RM, Mrozek E, Pan X, Summers TA, Shapiro CL, Chalmers JJ

Breast Cancer Res 16 R23 01/01/2014
Isolation and analysis of rare cells in the blood of cancer patients using a negative depletion methodology.

Wu Y, Deighan CJ, Miller BL, Balasubramanian P, Lustberg MB, Zborowski M, Chalmers JJ

Methods 64 169-82 12/01/2013
On-chip magnetic separation and encapsulation of cells in droplets.

Chen A, Byvank T, Chang WJ, Bharde A, Vieira G, Miller BL, Chalmers JJ, Bashir R, Sooryakumar R

Lab Chip 13 1172-81 03/21/2013
Open Gradient Magnetic Red Blood Cell Sorter Evaluation on Model Cell Mixtures.

Moore LR, Nehl F, Dorn J, Chalmers JJ, Zborowski M

IEEE Trans Magn 49 309-315 02/01/2013
Simultaneous, single particle, magnetization and size measurements of micron sized, magnetic particles.

Xu J, Mahajan K, Xue W, Winter JO, Zborowski M, Chalmers JJ

J Magn Magn Mater 324 4189-4199 12/01/2012

See Full List

Back to Researcher Search

Find a Researcher
Find a Clinical Trial

Please enter a keyword (i.e. Name, Research Interest) or choose a Research Program

By Name or Keyword

OR

By Research Program

Please enter a keyword (i.e. Name, Cancer Type) or choose a Principle Investigator

Jeffrey J Chalmers, PhD

College

Department/Division

Academic Title

Research Program

Research Interest

Education and Background

Office Location

Publications

Mechanotransduction Effects on Endothelial Cell Proliferation via CD31 and VEGFR2: Implications for Immunomagnetic Separation.

Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells.

Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery.

Multispectral Imaging Analysis of Circulating Tumor Cells in Negatively Enriched Peripheral Blood Samples.

Effect of surgical intervention on circulating tumor cells in patients with squamous cell carcinoma of the head and neck using a negative enrichment technology.

Multiparameter Evaluation of the Heterogeneity of Circulating Tumor Cells Using Integrated RNA In Situ Hybridization and Immunocytochemical Analysis.

Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells.

Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells.

Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells.

CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.

Tailoring the surface charge of dextran-based polymer coated SPIONs for modulated stem cell uptake and MRI contrast.

Feasibility study of red blood cell debulking by magnetic field-flow fractionation with step-programmed flow.

Heterogeneous atypical cell populations are present in blood of metastatic breast cancer patients.

Isolation and analysis of rare cells in the blood of cancer patients using a negative depletion methodology.

On-chip magnetic separation and encapsulation of cells in droplets.

Open Gradient Magnetic Red Blood Cell Sorter Evaluation on Model Cell Mixtures.

Simultaneous, single particle, magnetization and size measurements of micron sized, magnetic particles.

OR

OR

Search for Clinical Trials

Find a Scientific Publication

Jeffrey J Chalmers, PhD

College

Department/Division

Academic Title

Research Program

Research Interest

Education and Background

Office Location

Publications

Related Links

OR

OR

Search for Clinical Trials

Find a Scientific Publication