Jennifer L Leight, PhD
College of Engineering
Molecular Biology and Cancer Genetics
As a member of the Molecular Biology and Cancer Genetics Program at OSUCCC – James, Jennifer Leight, PhD, uses innovative biomaterials to investigate fundamental questions regarding the tumor microenvironment and the regulation of cancer cell function. She has also developed new methods for measuring matrix metalloproteinases (MMP) produced by cancer cells and cells in the microenvironment.Her recent research included designing a three-dimensional hydrogel system to probe whether pharmacological inhibition affected human melanoma cell proteolytic activity. As a result, her fellow researchers and she argue the importance of studying MMP activity with drug treatment and its possible implications for unwanted side effects. Dr. Leight has co-authored articles published in well-respected outlets, including Proceedings of the National Academy of Sciences, Advanced Healthcare Materials and Biomaterials. She has also presented at national meetings, including the Biomedical Engineering Society, Society for Biomaterials and American Society for Cell Biology.