Joanna L Groden, PhD
College of Medicine
Cancer Biology and Genetics
Molecular Biology and Cancer Genetics
Cancer, Adenomatous Polyposis Coli, Bloom Syndrome, Colorectal Cancer, Colonic Cancer, Adenoma, Microsatellite Instability
Joanna Groden, PhD, is a professor in the Department of Cancer Biology and Genetics at Ohio State and a member of the Molecular Biology and Cancer Genetics Program at the OSUCCC – James. She also serves as vice dean of research for Ohio State’s College of Medicine.Dr. Groden’s research focuses on the study of inherited disorders that increase susceptibility to cancer. In particular, her work explores Bloom syndrome—a disorder that decreases chromosome stability and increases susceptibility to cancer—as well as disorders that make people vulnerable to colorectal cancer, particularly familial adenomatous polyposis coli. She also explores the use of mouse models to learn more about the formation, diagnosis and treatment of human cancers. One of her recent studies determined microRNA 135b (miR-135b) to be a downstream effector of oncogenic pathways, which means it could be a target for colorectal cancer treatment. Dr. Groden has authored or co-authored many articles appearing in well-known publications, including Cancer Cell, Mutation Research and The American Journal of Pathology.