John S Gunn, PhD

John Gunn


College of Medicine



Academic Title


Research Program

Molecular Biology and Cancer Genetics

Research Interest

tularemia ● Gram-Negative Bacterial Infections ● Salmonella Infections, Animal ● Infection ● Salmonella Infections ● Typhoid Fever ● Carrier State ● Mutagenesis, Insertional

John Gunn, PhD, is a professor in the Department of Pediatrics at Ohio State, Nationwide Children’s Center for Microbial Pathogenesis, and a member of the Molecular Biology and Cancer Genetics Program at the OSUCCC – James, where his research centers on microbial resistance to innate immunity. In particular, he is focused on the macrophage as well as the mucosal surface.

In one of his studies, he is using a mouse model to determine if S. Typhi gallbladder carriage leads to cancer. If so, this finding could contribute significantly to early detection or prevention of gallbladder cancer. It also could indicate a broader relationship between chronic infections and cancer.

Dr. Gunn has authored or co-authored many articles in well-respected publications, including the Journal of Biological Chemistry, Frontiers in Microbiology, Antimicrobial Agents and Chemotherapy and International Journal of Pharmaceutics.

Office Location


700 Children's Drive, Columbus, OH 43205




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