Jon P Butchar, PhD

Jon Butchar

College

College of Medicine

Department/Division

Hematology

Academic Title

Res Asst Professor

Research Program

Leukemia Research

Research Interest

Infection, Leukemia, Lymphocytic, Chronic, B-Cell, tularemia, Cancer

Monocytes / macrophages can engulf or even directly kill antibody-coated tumor cells, and this is mediated largely through Fc-gamma receptors. These cells can also respond to pathogens such as bacteria or viruses by activation of Toll-like receptors. Such Toll-like receptor activation has been shown to enhance Fc-gamma receptor function. My work involves bringing pathogenesis and tumor immunotherapy together by studying the interactions between Fc-gamma receptor and Toll-like receptor signaling. The ultimate goal is to help improve the efficacy of antibody therapy.


Education and Background

Office Location

385C Wiseman Hall

400 W 12th Avenue, Columbus, Ohio 43210


614-366-0726

614-247-4575



Publications

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