Lalit Sehgal, MPhil, PhD
College of Medicine
Lalit Sehgal, PhD, is a translational scientist and an assistant professor in the Division of Hematology at the OSUCCC – James. He was trained as a human geneticist and specializes in developing strategies for personalized therapy for lymphoid malignancies.Dr. Sehgal’s research interests include indolent and aggressive B-cell Non-Hodgkin’s lymphomas and multiple myeloma. The focus of his laboratory is to understand the role of tumor microenvironment in the progression of B-cell lymphomas. The group has identified a subpopulation of tumor cells capable of initiating the bulk tumor, and they are trying to identify the therapeutic target unique to these initiating cells. He is also interested in understanding how non-coding RNA regulates epigenetic marks and contributes to drug resistance in lymphoma. He aims to translate the findings to the clinic through drug development. Dr. Sehgal’s work has been published in numerous hematologic journals such as Leukemia, Blood, Hematologica, British Journal of Hematology, Molecular Cancer Research and Journal of Cell Science, and he has presented his research at more than a dozen national and international conferences. Additionally, he has received multiple awards, including the Endowed Fellow Award for Excellence in lymphoma.