Lawrence S Kirschner, MD, PhD

Lawrence Kirschner


College of Medicine


Internal Medicine

Academic Title


Research Program

Molecular Biology and Cancer Genetics

Research Interest

Cancer, Carney Complex, Hyperplasia, Thyroid Cancer, Myxoma, Adrenocortical Carcinoma, Pituitary Cancer, Neurilemmoma, Loss of Heterozygosity, Cushing Syndrome

Dr. Kirschner's research is focused on endocrine tumor genetics, with specific interest in understanding how dysregulation of PKA contributes to tumorigenesis in cAMP-responsive tissues. Using a combination of in vivo mouse models and in vitro tissue culture work, his lab aims to understand how activated PKA cross-talks with a variety of other signaling pathways to produce tumors. As part of OSU’s thyroid cancer group, they have developed mouse models of benign and malignant follicular thyroid tumors which behave similarly to the human disease.

Education and Background

Office Location

579 McCampbell Hall

1581 Dodd Drive, Columbus, OH 43210




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