Meixiao Long, MD, PhD

Meixiao Long

College

COM

Department/Division

Hematology

Academic Title

Asst Professor

Research Program

Leukemia Research

Meixiao Long, MD, PhD, is a member of the Leukemia Research Program at the OSUCCC – James, where his research focuses primarily on developing immunotherapy strategies for the treatment of leukemia and lymphoid malignancies. More specifically, he explores the underlying mechanism of functional deficiency of tumor-targeting T cells and how to reverse this with small-molecule drugs that target key signaling pathways of immune cells.

Dr. Long has experience in studying T-cell immunity and works on the generation and characterization of mouse models to test immunotherapy approaches. He developed and optimized the protocols to monitor antigen-specific T-cell response in vivo in human subjects and animal models, which allow us detect and isolate T cells of very low frequency (up to one in ten million.) These provide powerful tools to characterize the functional and molecular features of antigen-specific T cells, enabling us to better understand T-cell immunity against tumor, viral and self-antigens and thus develop novel immunotherapy treatments.

He is involved in several long-term research projects at The Ohio State University under the direction of John C. Byrd, MD, including studying the effects of ibrutinib as an immunomodulatory drug to enhance anti-tumor T-cell response and combining targeted therapy and immunotherapy for the treatment of leukemia.

Dr. Long has co-authored numerous articles in peer-reviewed publications such as Immunity, Journal of Immunology, Blood and JAMA Oncology.


Education

  • Doctorate, China Medical University

    Shenyang, Liaoning Province (China)

  • Doctorate, University of Connecticut Health Center

    Farmington , CT (USA)

  • Doctorate, China Medical University

    Shenyang, Liaoning Province (China)

  • Doctorate, University of Connecticut Health Center

    Farmington , CT (USA)

Office Location

485 Wiseman

410 W 12th Ave, Columbus, OH 43210


614-293-2742

614-293-7484



Publications

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