Michael T Bailey, PhD
College of Dentistry
Molecular Carcinogenesis and Chemoprevention
Inflammation, Infection, Anxiety, Influenza, Human, Colitis, Orthomyxoviridae Infections, Campylobacter Infections, Enterobacteriaceae Infections
Dr. Bailey has a longstanding interest in understanding how commensal microbes impact immune system functioning, particularly during periods of endocrine activation. Studies from my laboratory, as well as others, indicate that gut microbes help to regulate the inflammatory response in both mucosal and systemic compartments. During disease or periods of endocrine activation, alterations in the composition of the gut microbiota can contribute to dysregulated inflammatory responses that can predispose individuals to certain types of cancer. Thus, the focus of his laboratory is to understand the mechanisms by which gut microbes can impact immune system functioning and to further determine whether alterations in diet or consumption of probiotic microbes can re-establish beneficial host-microbe interactions during periods of disease.