Parvathi Ranganathan, PhD
College of Medicine
Res Asst Professor
Dr. Ranganathan, PhD is a member of the Leukemia Research Program at the OSUCCC-James.
Dr. Ranganathan's primary research interest is to study the immunobiology of acute Graft-Versus-Host Disease (aGVHD) with the goal of developing selective immune suppression strategies that abrogate aGVHD while maintaining T-cell responses needed to preserve the beneficial graft-versus leukemia (GVL) effect. In addition, she studies the immunomodulatory role of cellular and circulating non-coding RNAs such as microRNAs, long non-coding RNAs and circular RNAs with emphasis on their roles in aGVHD pathogenesis. A second focus of her research is to develop novel targeted therapies in acute myeloid leukemia (AML).