Paul J Goodfellow, PhD
College of Medicine
Obstetrics & Gynecology
Molecular Biology and Cancer Genetics
Cancer, Endometrial Cancer, Microsatellite Instability, Multiple Endocrine Neoplasia Type 2a, Loss of Heterozygosity, Thyroid Cancer, Carcinoma, Colorectal Cancer, Multiple Endocrine Neoplasia Type 2b, Genetic Markers
The research of Paul Goodfellow, PhD, a professor in the Department of Obstetrics and Gynecology at Ohio State and a member of the OSUCCC – James Molecular Biology and Cancer Genetics Program, centers on understanding the role that loss of DNA-mismatch repair plays in uterine tumor initiation and progression, and on learning how key molecular events can be used to develop novel approaches to prevent and treat endometrial cancers. His group also investigates novel ovarian and breast cancer susceptibility factors.Dr. Goodfellow has published more than 200 papers in genetics and oncology specialty journals including New England Journal of Medicine, Science, Nature, American Society of Human Genetic, Journal of Clinical Oncology, Gynecologic Oncology, Journal of the National Cancer Institute and JAMA Oncology. He is the co-holder of two patents: one for a method of diagnosing, classifying and treating endometrial cancer and pre-cancer, and another for compositions, methods and kits to detect DICER-gene mutations.