Ramesh K Ganju, PhD

Ramesh Ganju

College

College of Medicine

Department/Division

Pathology

Academic Title

Professor

Research Program

Molecular Biology and Cancer Genetics

Research Interest

Cancer, Breast Cancer, Neoplasm Metastasis, Sarcoma, Kaposi, Carcinoma, Non-Small-Cell Lung

Ramesh Ganju, PhD, is a professor and vice chair of experimental pathology in the Department of Pathology at Ohio State, where he is also a researcher in the Molecular Biology and Cancer Genetics Program at the OSUCCC – James.

The major focus of Dr. Ganju’s laboratory is to elucidate mechanisms that regulate tumor growth and metastasis (spread). His team is also developing immune-based therapies for solid tumors. Dr. Ganju and colleagues have identified signaling pathways that regulate tumor growth, chemo-invasion and metastasis of tumor cells, especially in breast cancer.

In particular, his team has discovered several biomarkers and signaling molecules that regulate growth and metastasis of triple-negative breast cancer (TNBC), including fatty acid binding protein 5 and transient receptor potential vanilloid type-2 (TRPV2). One of his recent projects indicated for the first time that TRPV2 could be a good prognostic marker for TNBC and estrogen receptor alpha-negative (ERa-) breast cancer patients, especially among patients who receive chemotherapy.


Education and Background

Office Location

810 Biomedical Research Tower

460 W 12th Ave, Columbus, OH 43210


614-292-5539

614-247-0051



Publications

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