Ramesh K Ganju, PhD

Ramesh Ganju


College of Medicine



Academic Title


Research Program

Molecular Biology and Cancer Genetics

Research Interest

Breast Cancer, Lung Cancer, Neoplasm Metastasis, Inflammation, Tumor Microenvironment, Signal Transduction

Ramesh Ganju, PhD, is a professor and vice chair of experimental pathology in the Department of Pathology at Ohio State, where he is also a researcher in the Molecular Biology and Cancer Genetics Program at the OSUCCC – James.

The major focus of Dr. Ganju’s laboratory is to elucidate mechanisms that regulate tumor growth and metastasis (spread). His team is also developing immune-based therapies for solid tumors. Dr. Ganju and colleagues have identified signaling pathways that regulate tumor growth, chemo-invasion and metastasis of tumor cells, especially in breast cancer.

In particular, his team has discovered several biomarkers and signaling molecules that regulate growth and metastasis of triple-negative breast cancer (TNBC), including fatty acid binding protein 5 and transient receptor potential vanilloid type-2 (TRPV2). One of his recent projects indicated for the first time that TRPV2 could be a good prognostic marker for TNBC and estrogen receptor alpha-negative (ERa-) breast cancer patients, especially among patients who receive chemotherapy.

Office Location

810 Biomedical Research Tower

460 W 12th Ave, Columbus, OH 43210




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