Samir N Ghadiali, PhD

Samir Ghadiali

College

College of Engineering

Department/Division

Biomedical Engineering

Academic Title

Professor

Research Program

Molecular Biology and Cancer Genetics

Research Interest

Wounds and Injuries, Breast Cancer, hypercalcemia

As part of an NSF funded project, Dr. Ghadiali uses engineering, biophysical and molecular/cell biology techniques to identify how biomechanical properties of both cancer cells and the tumor microenvironment (TME) influence oncogenic epithelial to mesenchymal transition (EMT). Dr. Ghadiali also collaborates with Dr. Michael Ostrowski’s lab to investigate how remodeling of the extracellular matrix by stromal fibroblasts in the TME influences cancer cell invasion. He is using targeted gene silencing and biomechanical manipulation techniques to both mitigate breast cancer cell invasion/metastasis and to overcome EGFR TKI resistance in lung cancer cells.


Education and Background

Office Location

270 Bevis Hall

1080 Carmack Road, Columbus, OH 43210


614-292-7742

614-292-7301



Publications

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