Sissy M Jhiang, PhD
College of Medicine
Physiology & Cell Biology
Molecular Biology and Cancer Genetics
Thyroid Cancer, Cancer, Breast Cancer, Multiple Endocrine Neoplasia Type 2a, Glioma, Loss of Heterozygosity
Dr Jhiang current research interests are: (a) examine RET/PTC mediated signaling pathways in thyroid tumorigenesis and apply the finding to improve patients' care; (b) Investigate regulatory mechanisms of Na+/I- symporter(NIS) in thyroid cancer and breast cancer and apply the finding to develop strategies for radionuclide imaging and effective targeted therapy; (c) NIS as an imaging reporter gene to monitor gene delivery in gene therapy clinical trials; and (d) mechanobiology characterization in the process of cancer metastasis using one-of-the-kind instruments based on atomic force microscopy, magnetic tweezer, and photonic force microscopy (in collaboration with Dr. CH Menq at the Department of Mechanical Engineering). Thus, Dr. Jhiang's research areas involved in molecular biology, cellular biology, genetic engineered animal models, small animal imaging modalities, and nanobiotechnology.