Thomas J Scharschmidt, MD

College

College of Medicine

Department/Division

Orthopeadics

Academic Title

Assoc Professor - Clinical

Research Program

Molecular Biology and Cancer Genetics

Research Interest

Cancer ● Sarcoma ● Liposarcoma ● Wounds and Injuries ● Liposarcoma, Myxoid ● Soft Tissue Cancer ● Periostitis ● Hemangiopericytoma ● Chromosome Aberrations ● Chondrosarcoma

Thomas Scharschmidt, MD, is a member of the Molecular Biology and Cancer Genetics Program at OSUCCC – James, where his research focuses on adjuvant chemotherapy for management of soft tissue and bone sarcomas.

He also investigates outcomes of limb reconstructions, oncology implant design, molecular biology and mechanisms of disease.

One of his recent studies indicates connective tissue growth factor, a downstream effector of transforming growth factor-Beta, could enable targeted therapy.

Dr. Scharschmidt has co-authored many articles in well-respected publications, including Journal of Surgical Oncology, Applied Immunohistochemistry & Molecular Morphology, and Journal of the American Academy of Orthopaedic Surgeons.

Office Location

725 Prior Hall Cramblett Hall, Henry

376 W 10th Ave, Columbus, OH 43210

614-293-4420

614-293-3747

scharschmidt.5@osu.edu

Publications

Rapid return to function and stability with dual mobility components cemented into an acetabular reconstructive cage for large osseous defects in the setting of periacetabular metastatic disease.

Plummer D, Passen E, Alexander J, Vajapey S, Frantz T, Niedermeier S, Pettit R, Scharschmidt T

J Surg Oncol in press 03/25/2019
Are Joint Surgeons Being Adequately Compensated for Single-Component versus Double-Component Revision TKA? An Analysis of Relative Value Units.

Malik AT, Scharschmidt TJ, Li M, Jain N, Khan SN

J Knee Surg in press 03/12/2019
Aneursymal Bone Cyst: An Uncommon Paraspinal Tumor in Children.

Shah N, Scharschmidt T, Fung B, Conces M, Setty BA

J Pediatr Hematol Oncol 41 e129-e131 03/01/2019
Decreasing Room Traffic in Orthopedic Surgery: A Quality Improvement Initiative.

DiBartola AC, Barron C, Smith S, Quatman-Yates C, Chaudhari AMW, Scharschmidt TJ, Moffatt-Bruce SD, Quatman CE

Am J Med Qual in press 1062860618821180 01/17/2019
Oncologic reconstruction of the proximal humerus with a reverse total shoulder arthroplasty megaprosthesis.

Grosel TW, Plummer DR, Mayerson JL, Scharschmidt TJ, Barlow JD

J Surg Oncol 118 867-872 11/01/2018
Factors associated with post-operative sepsis following surgery for spinal tumors: An analysis of the ACS-NSQIP database.

Malik AT, Jain N, Scharschmidt TJ, Mayerson JL, Khan SN

Clin Neurol Neurosurg 172 1-7 09/01/2018
When is hemiarthroplasty preferable to intramedullary prophylactic fixation of metastatic disease of the proximal femur?

Lin JS, Santiago-Torres JE, Everhart JS, Zayan NE, Mayerson JL, Scharschmidt TJ

J Surg Oncol 117 811-812 03/01/2018
Perioperative Allogeneic Red Blood-Cell Transfusion Associated with Surgical Site Infection After Total Hip and Knee Arthroplasty.

Everhart JS, Sojka JH, Mayerson JL, Glassman AH, Scharschmidt TJ

J Bone Joint Surg Am 100 288-294 02/21/2018
Does Surgeon Volume Affect Outcomes Following Primary Total Hip Arthroplasty? A Systematic Review.

Malik AT, Jain N, Scharschmidt TJ, Li M, Glassman AH, Khan SN

J Arthroplasty 33 3329-3342 01/01/2018
When is hemiarthroplasty preferable to intramedullary prophylactic fixation of malignant lesions of the proximal femur?

Lin JS, Santiago-Torres JE, Everhart JS, Zayan NE, Mayerson JL, Scharschmidt TJ

J Surg Oncol 116 1132-1140 12/01/2017
Clinical trial enrollment of adolescents and young adults with sarcoma.

Davis LE, Janeway KA, Weiss AR, Chen YE, Scharschmidt TJ, Krailo M, Glade Bender JL, Kopp LM, Patel SR, Schwartz GK, Horvath LE, Hawkins DS, Chuk MK, Reinke DK, Gorlick RG, Randall RL

Cancer 123 3434-3440 09/15/2017
Clinical trial enrollment of adolescents and young adults with sarcoma.

Davis LE, Janeway KA, Weiss AR, Chen YE, Scharschmidt TJ, Krailo M, Glade Bender JL, Kopp LM, Patel SR, Schwartz GK, Horvath LE, Hawkins DS, Chuk MK, Reinke DK, Gorlick RG, Randall RL

Cancer 123 3434-3440 09/15/2017
TGF-β and CTGF are Mitogenic Output Mediators of Wnt/β-Catenin Signaling in Desmoid Fibromatosis.

Varghese S, Braggio DA, Gillespie J, Toland AE, Pollock R, Mayerson J, Scharschmidt T, Iwenofu OH

Appl Immunohistochem Mol Morphol 25 559-565 01/01/2017
Patterns of major wound complications following multidisciplinary therapy for lower extremity soft tissue sarcoma.

Miller ED, Mo X, Andonian NT, Haglund KE, Martin DD, Liebner DA, Chen JL, Iwenofu OH, Chakravarti A, Scharschmidt TJ, Mayerson JL, Pollock RE, Xu-Welliver M

J Surg Oncol 114 385-91 09/01/2016
Targeted Chemotherapy in Bone and Soft-Tissue Sarcoma.

Harwood JL, Alexander JH, Mayerson JL, Scharschmidt TJ

Orthop Clin North Am 46 587-608 10/01/2015
Novel Clonal t(2;4) (q23;p14) Secondary Cytogenetic Abnormality in a Primary Myxoid Liposarcoma.

Kiyani A, Heerema NA, Mayerson JL, Scharschmidt TJ, Iwenofu OH

Appl Immunohistochem Mol Morphol 23 538-40 08/01/2015
Surgical management of soft tissue sarcomas: extremity sarcomas.

Chao AH, Mayerson JL, Chandawarkar R, Scharschmidt TJ

J Surg Oncol 111 540-5 04/01/2015
Diagnosis and Management of Soft-tissue Masses.

Mayerson JL, Scharschmidt TJ, Lewis VO, Morris CD

Instr Course Lect 64 95-103 01/01/2015
Diagnosis and Management of Soft-tissue Masses.

Mayerson JL, Scharschmidt TJ, Lewis VO, Morris CD

J Am Acad Orthop Surg 22 742-50 11/01/2014
The character of gene expression of human periosteum used to form new tissue in allograft bone.

Kemppainen J, Yu Q, Alexander J, Jacquet R, Scharschmidt T, Landis W

Connect Tissue Res 55 Suppl 1 146-9 08/01/2014
Is orthopedics more competitive today than when my attending matched? An analysis of National Resident Matching Program data for orthopedic PGY1 applicants from 1984 to 2011.

Karnes JM, Mayerson JL, Scharschmidt TJ

J Surg Educ 71 530-42 07/01/2014

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Thomas J Scharschmidt, MD

College

Department/Division

Academic Title

Research Program

Research Interest

Office Location

Publications

Rapid return to function and stability with dual mobility components cemented into an acetabular reconstructive cage for large osseous defects in the setting of periacetabular metastatic disease.

Are Joint Surgeons Being Adequately Compensated for Single-Component versus Double-Component Revision TKA? An Analysis of Relative Value Units.

Aneursymal Bone Cyst: An Uncommon Paraspinal Tumor in Children.

Decreasing Room Traffic in Orthopedic Surgery: A Quality Improvement Initiative.

Oncologic reconstruction of the proximal humerus with a reverse total shoulder arthroplasty megaprosthesis.

Factors associated with post-operative sepsis following surgery for spinal tumors: An analysis of the ACS-NSQIP database.

When is hemiarthroplasty preferable to intramedullary prophylactic fixation of metastatic disease of the proximal femur?

Perioperative Allogeneic Red Blood-Cell Transfusion Associated with Surgical Site Infection After Total Hip and Knee Arthroplasty.

Does Surgeon Volume Affect Outcomes Following Primary Total Hip Arthroplasty? A Systematic Review.

When is hemiarthroplasty preferable to intramedullary prophylactic fixation of malignant lesions of the proximal femur?

Clinical trial enrollment of adolescents and young adults with sarcoma.

Clinical trial enrollment of adolescents and young adults with sarcoma.

TGF-β and CTGF are Mitogenic Output Mediators of Wnt/β-Catenin Signaling in Desmoid Fibromatosis.

Patterns of major wound complications following multidisciplinary therapy for lower extremity soft tissue sarcoma.

Targeted Chemotherapy in Bone and Soft-Tissue Sarcoma.

Novel Clonal t(2;4) (q23;p14) Secondary Cytogenetic Abnormality in a Primary Myxoid Liposarcoma.

Surgical management of soft tissue sarcomas: extremity sarcomas.

Diagnosis and Management of Soft-tissue Masses.

Diagnosis and Management of Soft-tissue Masses.

The character of gene expression of human periosteum used to form new tissue in allograft bone.

Is orthopedics more competitive today than when my attending matched? An analysis of National Resident Matching Program data for orthopedic PGY1 applicants from 1984 to 2011.

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