A New Role for Lyn in the CLL Microenvironment.

Dong S, Byrd JC
Cancer Cell 30 511-512 01/10/2016


The role of Lyn, both a positive and a negative regulator of B and myeloid cells, in chronic lymphocytic leukemia (CLL) has not been well characterized. In this issue of Cancer Cell, Nguyen et al. demonstrated that Lyn in macrophages rather than in CLL cells is critical for the malignancy.

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