Controllable Self-Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting.

Li H, Zhang K, Pi F, Guo S, Shlyakhtenko L, Chiu W, Shu D, Guo P
Adv Mater 28 7501-7 09/01/2016


RNA tetrahedral nanoparticles with two different sizes are successfully assembled by a one-pot bottom-up approach with high efficiency and thermal stability. The reported design principles can be extended to construct higher-order polyhedral RNA architectures for various applications such as targeted cancer imaging and therapy.

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