How Long of a Dynamic 3'-Deoxy-3'-[18F]fluorothymidine ([18F]FLT) PET Acquisition Is Needed for Robust Kinetic Analysis in Breast Cancer?
Zhang J, Liu X, Knopp MI, Ramaswamy B, Knopp MV
Mol Imaging Biol in press 07/09/2018
PURPOSE: To quantitatively evaluate the minimally required scanning time of 3'-deoxy-3'-[
PROCEDURES: Within a therapeutic intervention trial, 26 breast tumors of 8 breast cancer patients were analyzed from 30-min dynamic [
RESULTS: The correlation of kinetic parameters between the gold standard and the abbreviated dynamic data series increased with longer T
CONCLUSIONS: This study indicates that a 16-min dynamic PET acquisition appears to be sufficient to provide accurate [