Intra-Abdominal and Abdominal Wall Desmoid Fibromatosis.

Howard JH, Pollock RE
Oncol Ther 4 57-72 01/01/2016

Abstract

Desmoid fibromatosis is a rare but locally aggressive tumor comprised of myofibroblasts. Desmoids do not have the ability to metastasize but can cause significant morbidity and mortality by local invasion. These tumors may occur throughout the body, but are commonly found on the abdominal wall and within the intestinal mesentery. Desmoids in these areas may cause unique clinical problems for physicians and patients. Mutations in either the β-catenin or the

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