Melanoma-associated mutants within the serine-rich domain of PAK5 direct kinase activity to mitogenic pathways.

LaPak KM, Vroom DC, Garg AA, Guan X, Hays JL, Song JW, Burd CE
Oncotarget 9 25386-25401 05/22/2018

Abstract

The overexpression and hyperactivity of p21-activated serine/threonine kinases (PAKs) is known to facilitate tumorigenesis; however, the contribution of cancer-associated

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