Salvage laryngectomy following organ-preservation therapy - An evidence-based review.
Silverman DA, Puram SV, Rocco JW, Old MO, Kang SY
Oral Oncol 88 137-144 01/01/2019
Salvage total laryngectomy is often indicated in patients with recurrent or persistent laryngeal cancer after radiation or chemoradiation treatment. This article reviews and discusses key considerations regarding salvage laryngectomy. Within this article, a review of the salvage laryngectomy incidence in the major organ preservation trials, survival rates, predictors of outcomes, complication rates, and the roles of elective neck dissection and free tissue transfer for reconstruction in patients undergoing salvage laryngectomy is provided.Full Text