The influence of genetic susceptibility and calcium plus vitamin D supplementation on fracture risk.

Wang Y, Wactawski-Wende J, Sucheston-Campbell LE, Preus L, Hovey KM, Nie J, Jackson RD, Handelman SK, Nassir R, Crandall CJ, Ochs-Balcom HM
Am J Clin Nutr 105 970-979 01/01/2017

Abstract

Fracture is a complex trait, affected by both genetic and environmental factors. A meta-analysis of genome-wide association studies (GWASs) identified multiple bone mineral density (BMD) and fracture-associated loci.

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