Venetoclax Adds a New Arrow Targeting Relapsed CLL to the Quiver.

Rogers KA, Byrd JC
Cancer Cell 29 3-4 01/11/2016


Inhibitors of B cell receptor signaling substantially changed the treatment of chronic lymphocytic leukemia as the first targeted agents to enter routine clinical practice. A recent paper by Roberts and colleagues describes an additional therapeutic target by reporting encouraging clinical results with venetoclax, an inhibitor of the antiapoptotic protein BCL2.

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