The Toland lab studies genetic susceptibility to cancer with a focus on colon and cutaneous squamous cell carcinoma (cSCC) and particular interest on uncovering the “missing heritability” for cancer risk. We utilize mouse models, in vitro models, human tumors and human population studies to identify gene-gene interactions important in cancer risk. We have additional projects to identify biomarkers and therapeutic targets for metastatic cSCC and to classify variants of uncertain significance in BRCA1/2 and other genes important in hereditary breast cancer.
Office Phone: 247-8185
Lab Phone: 247-7309