BSSR Director: Heather Hampel, MS, LGC
OSUCCC Clinical Research Operations Director: Nancy Single, PhD
The broad mission of the OSUCCC Biospecimen Services Shared Resource (BSSR) is to support cutting edge translational research to advance the prevention, diagnosis and treatment of cancer. The BSSR is comprised of three arms as described below.
Arm 1: Total Cancer Care (TCC)
PI: Heather Hampel, MS, LGC
TCC Operations Director: Laura Monovich, MBA
TCC Consent Director: Cecilia DeGraffinreid, MHS
The first arm is a universal consenting and biobanking protocol, Total Cancer Care (TCC). Total Cancer Care® allows for the collection of blood in conjunction with clinically indicated draws and remnant tissue from surgical procedures from patients 18 years of age and older, with and without cancer, who are seen at The James. Participating patients also consent to the use of their medical and genomic information. This lifetime consent allows for recontacting patients for an annual health status update if needed, and/or to notify them about opportunities to participate in clinical trials for which they are eligible. Plasma, serum and DNA, along with snap frozen tissue are stored for future research. The collected biospecimens are stored at the College of American Pathologists approved BSSR Biorepository located at OSU's Polaris Innovation Centre. Researchers may receive samples and data with subject identifiers with prior IRB-approval, or de-identified and coded-limited data sets without additional prior IRB approvals.
TCC is the single protocol used by the Oncology Research Information Exchange Network (ORIEN), which was formed through a partnership between the OSUCCC – James and Moffitt Cancer Center in Tampa, Fla., as a collaboration to accelerate cancer research discoveries that can translate to more effective clinical care. Using TCC, ORIEN will create a collaborative, “rapid-learning” environment that will share de-identified patient data to hasten the development of targeted treatments and more quickly match eligible patients to clinical trials. The network currently numbers 17 cancer centers.
Arm 2: Prospective Procurement
Scott Scrape, MD
The second arm of the BSSR provides prospectively procured tissue and fluid biospecimens from surgical procedures to OSUCCC investigators who are in need of pathology samples that have not been previously banked. Samples are processed according to protocol.
Arm 3: BSSR Biorepository
BSSR Biorepository Manager: Jason Bacher, BA
Arm 3 of the BSSR provides biospecimen processing and banking services to investigators for IRB-approved and grant-funded projects, including but not limited to SPOREs, P01s, statewide initiatives and Pelotonia-funded initiatives.