Biospecimen Services

BSSR Director: Heather Hampel, MS, CGC
OSUCCC Clinical Research Administration Director: Nancy Single, PhD
BSSR Operations Director: Laura Monovich, MBA
BSSR Consent Manager: Cecilia DeGraffinreid

The broad mission of the OSUCCC Biospecimen Services Shared Resource (BSSR) is to support cutting edge translational research to advance the prevention, diagnosis and treatment of cancer.

The BSSR is comprised of two arms: the first arm is for collection using a universal consenting and biobanking protocol, Total Cancer Care (TCC). The TCC protocol includes a broad informed consent allowing for access to pathologic and clinical data for life, with the ability to re-contact patients at any time for clinical follow-up and/or to offer participation in clinical trials for which they are eligible. The collected tissues are stored at the BSSR biobank located at OSU's Nationwide Children’s Hospital Biopathology Center, which is both NCI funded and approved by the College of American Pathologists. 

The second arm of the BSSR provides prospectively procured biospecimens to OSUCCC investigators from all five OSUCCC research programs who are in need of pathology samples. Researchers may receive samples and data with subject identifiers with prior IRB-approval, or de-identified and coded-limited data sets without additional prior IRB approvals. 

Total Cancer Care® (TCC) is a new, universal consent and biorepository protocol that allows for the collection of blood in conjunction with clinically indicated draws and remnant tissue from surgical procedures from patients 18 years of age and older, with and without cancer, who are seen at The James. The study of blood and tissue will help researchers find better ways to prevent, detect and treat cancer. 

Participating patients also consent to the use of their medical and genomic information. This lifetime consent allows for recontacting patients for an annual health status update if needed, and/or to notify them about opportunities to participate in clinical trials for which they are eligible.

Plasma, serum and DNA, along with snap frozen tissue. are stored for future research. Specimens are stored in The James Biobank at Nationwide Children’s Hospital (NCH) Biopathology Center, under the direction of Dr. Nilsa Ramirez. NCH is an international leader in biobanking.

TCC is the single protocol used by the Oncology Research Information Exchange Network (ORIEN), which was formed through a partnership between the OSUCCC – James and Moffitt Cancer Center in Tampa, Fla., as a collaboration to accelerate cancer research discoveries that can translate to more effective clinical care. Using TCC, ORIEN will create a collaborative, “rapid-learning” environment that will share de-identified patient data to hasten the development of targeted treatments and more quickly match eligible patients to clinical trials. 

Contact Us:

Arm 1 – TCCP

Heather Hampel, MS
Polaris Parkway, 2001
2001 Polaris Pkwy
Columbus, OH 43240



Arm 2 – Prospectively Procured Biospecimen Samples

Scott Scrape, MD
Polaris Innovation Centre
2001 Polaris Parkway
Columbus, OH  43240

Phone: 614-366-1579
Fax: 293-7013 

Please enter a keyword (i.e. Name, Research Interest) or choose a Research Program


Please enter a keyword (i.e. Name, Cancer Type) or choose a Principle Investigator


Search for Clinical Trials

Find a Scientific Publication