Director: Larry J. Schaaf, PhD

The Clinical Treatment Unit and the Clinical Trials Processing Laboratory Shared Resource (CTU/CTPLSR) enable OSUCCC – James investigators to conduct successful phase clinical translational research in a methodologically sound, expedient and cost-effective manner.

The CTU is an ambulatory phase I unit in the OSUCCC – James that specializes in treating early clinical trial patients who require intense monitoring or complex correlative sample collection and processing. 

The CTPL enhances research quality by providing dedicated staff for high-volume procurement, processing, storage, delivery and shipment of research specimens critical to the correlative studies component of OSUCCC – James clinical trials.

The CTU/CTPLSR experts work closely with other OSUCCC – James Shared Resources, including the Pharmacoanalytical, Leukemia Tissue Bank and Biorepository and Biospecimen Shared Resources. These collaborations provide protocol review and feasibility assessment, specimen kit assembly and specimen distribution to internal and external research laboratories.


The CTU/CTPLSR Shared Resource offers investigators at OSUCCC – James access to experts to assist researchers with conducting successful clinical translational research.

  • CTU/CTPLSR Director: Larry J. Schaaf, PhD
  • CTU Nurse Manager: Sara Vetter, BSN, RN
  • Clinical Laboratory Manager: Megan Jukich, BA

Larry J. Schaaf, PhD, director of the CTU/CTPLSR, is an adjunct professor in The Ohio State University College of Pharmacy whose expertise is backed by more than 25 years of experience in conducting and analyzing phase I and phase II clinical correlative trials.

With an extensive background in pharmacokinetics and early clinical trials, Dr. Schaaf has played a key role in the development and clinical application of multiple, widely used anti-cancer drugs, including irinotecan, exemestane and epirubicin.

Dr. Schaaf received his doctorate in pharmaceutical sciences from the University of Arizona, his master’s degree in clinical pharmacy from the University of Iowa and his Bachelor of Science degree in pharmacy from the same university.

He has authored or co-authored more than 50 peer-reviewed papers describing the correlative aspects of early translational trials.

Sara Vetter, MS, BSN, RN, is the CTU Nurse Manager. Sara received her Master’s and Bachelor's degrees from The Ohio State University. She has ten years of experience in both in-patient and out-patient oncology nursing.

Megan Jukich, BA, is the CTPL’s Clinical Laboratory Manager and works with the shared resource director, Larry Schaaf, PhD, as well as with the OSUCCC–James Clinical Trials Office to coordinate research studies supported by the CTU/CTPLSR.

Megan’s expertise lies in procuring, processing, storing and distributing research specimens. She oversees daily operations of CTPL laboratories, which includes: hiring and training personnel; monitoring sample processing, laboratory safety, equipment maintenance, supply inventory and specimen shipments; and ensuring that all clinical laboratory technologists remain compliant with all required university and GCP certifications.

Megan participates in protocol feasibility/logistics reviews, assists with writing standard operating procedures and represents the CTPL on a subcommittee that monitors issues related to research specimen collection and processing.

Prior to her role with the CTU/CTPLSR, she was a research assistant in the Biopathology Center tissue bank at Nationwide Columbus Children’s Hospital.

Contact Us

CTU/CTPL Shared Resource
OSUCCC – James
460 West 10th Avenue, Room 502B
Columbus, Ohio 43210
Director: Larry J. Schaaf, PhD
Office: Room 405 Biomedical Research Tower
Phone: 614-293-6851

Rooms B501-B504
Nurse Manager: Sara Vetter, MS, BSN, RN
Office: Room A513 James Cancer Hospital and Solove Research Institute
Phone: 614-293-6641
Nursing Unit Phone: 614-293-6650
CTU Availability: Monday – Friday
Hours: 7:30 a.m. – 7:30 p.m.
Weekends and holidays as required

Clinical Laboratory Manager: Megan Jukich, BA
Office:  Room B502B
Phone: 614-293-3038

James Cancer Hospital and Solove Research Institute CTPL Research Labs
Room B502
460 West 10th Avenue
Phone: 614-293-6030
Room 234C (CTU Lab)
Phone: 614-293-6659
CTPL Pager: 346-2488
Availability: Monday-Friday
Hours: 7:30 a.m. – 11 p.m.
On call, Weekends and Holidays

Martha Morehouse Medical Plaza CTPL Research Lab
Room 308
2050 Kenny Road
Availability: Monday – Friday
Hours: 8 a.m. – 4:30 p.m.
Phone: 614-366-7478 
Pager: 346-7678

Brain and Spine Hospital CTPL Research Lab
Room 234C
300 West 10th Avenue
Phone:  614-293-6659
Pager:  691-2460
Availability:  Monday - Friday
Hours:  8 a.m. - 4:30 p.m.

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