Expertise

The CPMPSR is located in Ohio State’s College of Veterinary Medicine and has access to veterinary pathology expertise from 13 board certified veterinary pathologists in the Department of Veterinary Biosciences. Additional expertise is available to CPMPSR clients by veterinary radiologists, ophthalmologists and cardiologists in the College of Veterinary Medicine.

  • CPMPSR Director: Krista M.D. La Perle, DVM, PhD, Dipl. ACVP

  • PMPSR Associate Director: Sue E. Knoblaugh, DVM, Dipl. ACVP

  • CPMPSR Comparative Pathologist: Kara N. Corps, DVM, PhD, Dipl. ACVP

  • Medical Laboratory Technologist: Jody Sneddon, MT (ASCP) SH

  • Research Assistant: Julie Rectenwald, AHT, MLT

  • Lab Demonstrator (virtual microscopy): Jenny Bolon, RVT

  • Histology/Immunohistochemistry Laboratory Manager: David Hart, BS, HT (ASCP)

  • Histotechnologist: Molly Beardsley, BS, RVT, HT (ASCP)

  • Histotechnologist: Chelssie Breece, BS

  • Histotechnologist: Tessa VerStraete, AA, BS

  • Immunohistotechnician: Florinda Jaynes, HT (ASCP)

Krista M.D. La Perle, DVM, PhD, Dipl. ACVP, is the CPMPSR director and a professor at The Ohio State University.

As CPMPSR Director, Dr. La Perle oversees all CPMPSR operations and projects, including pre-submission consultations, macroscopic lesion interpretation, histologic tissue evaluation, clinical pathology data interpretation and final report preparation. She also meets with investigative staff to discuss findings, demonstrate pertinent lesions, recommend ancillary tests and plan subsequent studies.

Dr. La Perle is an expert in veterinary comparative pathology: she completed her postdoctoral training in veterinary anatomic pathology at Ohio State and is board certified by the American College of Veterinary Pathologists. She earned her DVM from North Carolina State University and her PhD in Experimental and Molecular Pathology from Ohio State University, where her National Institutes of Health-funded research focused on animal models of thyroid cancer and developing gene therapy strategies of sodium/iodide symporter-mediated radionuclide imaging and therapy for cancer.

Prior to her position as the CPMPSR Director, Dr. La Perle established the Genetically Engineered Mouse Phenotyping Service and was director of the Laboratory of Comparative Pathology for Memorial Sloan-Kettering Cancer Center, Weill Medical College of Cornell University and Rockefeller University in New York City.

Sue E. Knoblaugh, DVM, Dipl. ACVP, is the CPMPSR Associate Director and an Assistant Professor at The Ohio State University.

Dr. Knoblaugh is a board certified veterinary pathologist with expertise in mouse pathology. She has considerable experience with genetically modified mice and the use of mouse models in the translational study of human disease, particularly models of inflammation, infectious disease and cancer She earned her DVM degree from the College of Veterinary Medicine at the Ohio State University, and received her post-graduate training in comparative pathology and laboratory animal pathology at the University of Washington in the department of Comparative Medicine. Prior to her recruitment to Ohio State, she was a comparative pathologist with the Comparative Medicine Shared Resource for 10 years at The Fred Hutchinson Cancer Research Center in Seattle, Washington.

Dr. Knoblaugh shares responsibility for all projects with Drs. Krista La Perle and Kara Corps, including pre-submission consultations, macroscopic lesion interpretation, histologic tissue evaluation, clinical pathology data interpretation and final report preparation. She also meets with investigative staff to discuss findings, demonstrate pertinent lesions, recommend ancillary tests and plan subsequent studies.

Kara N. Corps, DVM, PhD, Dipl. ACVP, is a comparative pathologist with the CPMPSR and an Assistant Professor at The Ohio State University.

Dr. Corps is a board certified veterinary pathologist with expertise in toxicologic and comparative pathology of animal models. She earned her DVM degree from Michigan State University and completed a MS in Comparative Medicine and Integrative Biology while in veterinary school. She received her post-graduate training in anatomic pathology at North Carolina State University and earned her PhD in neuroscience at the National Institutes of Health.

Dr. Corps shares responsibility for all projects with Drs. Krista La Perle and Sue Knoblaugh, including pre-submission consultations, macroscopic lesion interpretation, histologic tissue evaluation, clinical pathology data interpretation and final report preparation. She also meets with investigative staff to discuss findings, demonstrate pertinent lesions, recommend ancillary tests and plan subsequent studies.

Jody Sneddon, MT (ASCP) SH, is a medical laboratory technologist for the CPMPSR.

With over 31 years of experience working in clinical pathology laboratories at Nationwide Children’s Hospital, Sneddon processes all clinical pathology specimens for in-house analysis, submits specimens to reference laboratories, reports clinical pathology results to investigators and pathologists and archives results and blood smears/cytology slides. Sneddon received her BS in Medical Technology from Ohio State and is certified as a Medical Technologist and a Specialist in Hematology from the American Society for Clinical Pathology.

Julie Rectenwald, AHT, MLT, research assistant, is an expert in coordinating histopathology for good laboratory practice (GLP) animal studies and has over 25 years of experience in the field.

Rectenwald processes samples, performs gross dissections, collects blood samples, weighs animals and tissues, identifies gross lesions, and harvests and trims tissues for histology. Additionally, she takes digital gross photographs and performs radiography, offers investigators instruction on tissue collection, fixation and trimming, and assists investigators with organizing and coordinatinganimal studies. Rectenwald received Associate of Applied Sciences degrees in Animal Health Technology and Medical Laboratory Technology from Columbus Technical Institute and Columbus State Community College, Columbus, Ohio, respectively.

Jenny Bolon, RVT, is a veterinary technologist and virtual microscopy lab demonstrator. She performs digital slide scanning with the Leica ScanScope XT. Prior to joining the CPMPSR and the Department of Veterinary Biosciences in December 2013, Bolon supported radiographic, fluoroscopic and MRI imaging of Ohio State Veterinary Medical Center patients for more than 23 years.

David Hart, BS, HT (ASCP), manages the histology/immunohistochemistry laboratory. A histotechnologist certified by the American Society of Clinical Pathologists (ASCP), Hart has more than 17 years of experience in all aspects of histology/immunohistochemistry and is responsible for technical and administrative oversight of the CPMPSR histology/immunohistochemistry lab.

Hart received his BS in Animal Science from the Ohio State University.

Molly Beardsley, BS, RVT, HT (ASCP), histotechnologist, has more than 10 years of expertise in embedding, sectioning and performing routine and special histochemical stains. Beardsley received her BS in Business Administration from the Ohio State University, her AA in Veterinary Technology and a Histology Certificate from Columbus State Community College, Columbus, Ohio, and she is certified by the American Society of Clinical Pathologists (ASCP).

Chelssie Breece, BS, histotechnologist, has more than 6 years of expertise in embedding, sectioning and performing routine, special histochemical and immunohistochemical stains. Breece received her BS in Forensics from the Ohio State University. She also has previous work experience in the OSU Germ Free Laboratory and at the Ohio Department of Agriculture Animal Disease Diagnostic Laboratory.

Tessa VerStraete, BS, RVT, histotechnologist, has almost 2 years of expertise in embedding, sectioning and performing routine histochemical stains, as well as gross dissections of animal models. VerStraete received her BS in Animal Science from the Ohio State University and her AA in Veterinary Technology from Columbus State Community College.

Florinda Jaynes, HT (ASCP), immunohistotechnician, offers investigators almost 40 years of experience in histology and immunohistochemistry. She is responsible for all aspects of the CPMPSR’s immunohistochemistry, including optimizing antigen retrieval techniques, novel antibodies and numerous detection methods. Jaynes is certified by the American Society of Clinical Pathologists (ASCP).

Cross-Institutional Work

The CPMPSR is used primarily by OSUCCC – James researchers and other investigators at Ohio State and affiliated institutions.

Contact Us

Comparative Pathology & Mouse Phenotyping Shared Resource Main Laboratory

Ohio State’s College of Veterinary Medicine
467/471 Veterinary Medicine Academic Building
1900 Coffey Rd.
Columbus, Ohio 43210

Phone: 614-247-8122
Email: CPMPSR@cvm.osu.edu

Availability: Monday – Friday
Hours: 8 a.m. – 5 p.m.

Main Histology/Immunohistochemistry Laboratory

Ohio State’s College of Veterinary Medicine
302 Goss Laboratory
1925 Coffey Rd.
Columbus, Ohio 43210

Phone: 614-292-3327
Email: CPMPSR@cvm.osu.edu

Availability: Monday – Friday
Hours: 8 a.m. – 5 p.m.

Digital Microscopy and Image Analysis Suite

Ohio State’s College of Veterinary Medicine
310 Goss Laboratory
1925 Coffey Rd.
Columbus, Ohio 43210

Phone: 614-247-4795
Email: CPMPSR@cvm.osu.edu

Availability: Monday – Friday
Hours: 8 a.m. – 5 p.m.

Six-Headed Microscope Laboratory

933 Biomedical Research Tower
460 W. 12th Ave.
Columbus, Ohio 43210

Phone: 614-247-6879
Email: CPMPSR@cvm.osu.edu

Availability: Scheduling upon request
Hours: Scheduling upon request

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