Microscopy


Director: Paul Stodley, PhD
Assistant Director: Sara Cole, PhD

The Microscopy Shared Resource (MSR) provides timely and high quality service to support OSUCCC investigators in a convenient, central location. Instruments, expert technical advice and training support a variety of sophisticated approaches in cancer research. The MSR provides a critical shared resource for cancer investigators to translate knowledge of cancer biology to new treatments against cancer.

MSR’s goals

  • Assist OSUCCC – James researchers with their microscopy needs
  • Provide access and training to technology that pushes the frontiers of cancer research      
  • Foster learning and increase understanding of microscopy

Expertise

The Microscopy Shared Resource (MSR) facilitates cancer research by providing an accessible centrally-organized resource with technical support for light and electron microscopy. Highly qualified faculty and staff provide training and advice for sample preparation, sample processing, basic microscopy, and advanced training for imaging live samples. The MSR, a part of the larger Campus Microscopy and Imaging Facility (CMIF) under the OSU Office of Research, is managed by the OSUCCC. The MSR is located within OSUCCC space in the Biomedical Research Tower. The ability to offer competitive pricing and exceptional service can be largely attributed to the generous support of outstanding institutional resources, including partnerships with the OSUCCC, the Office of Research, and state and federal grants. The Microscopy Shared Resource (MSR) gives researchers access to a full range of highly-specialized microscopes. MSR experts provide consultation and support for experimental design and implementation to support high-level cancer research with the latest microscopy techniques.

Paul Stoodley, PhD, Director. Dr. Stoodley is a Professor of Microbial Infection and Immunity and Orthopaedics in the College of Medicine, has previous experience running imaging facilities for the Center for Genomic Sciences in Pittsburgh, PA, and at the NSF Center for Biofilm Engineering in Bozeman, MT. Dr. Stoodley has used confocal and electron microscopy extensively in his research and has developed a number of custom designed flow cell systems for live-cell imaging under physiological flow conditions. He has also developed methods for direct observation of clinical specimens and is co-inventor of patented methods for using reflected confocal microscopy to differentiate implant surfaces and matrix materials. These techniques will be developed in collaboration with the MSR team and our users to expand the capabilities of the MSR for use by OSUCCC researchers.

Sara Cole, PhD, Associate Director. Dr. Cole received her PhD from the Department of Microbiology and Immunology at The Pennsylvania State University College of Medicine. She has over 20 years’ experience in cancer research that has included the use of fluorescent and chromogenic labeling technologies and practical experience with wide-filed, confocal and live cell imaging techniques. Dr. Cole joined the MSR in 2010 and oversees the live-cell imaging and Multiphoton systems.

Angela Blissett, PhD, CEMT, Electron Microscopist. Dr. Blissett is an Electron Microscopist at the MSR specializing in both transmission and scanning electron microscopy. She earned her doctoral degree in Biophysics at The Ohio State University in 2011 and joined the MSR in 2016. she is a Certified Electron Microscopy Technologist (CEMT) with over 10 years’ experience in TEM imaging and sample preparation. Dr. Blissett also works with researchers interested in SEM sample processing and imaging.

Brian Kemmenoe, BS, Senior Electron Microscopist. Mr. Kemmenoe received his bachelor’s degree in applied biology from North East London Polytechnic, England and brings nearly 30 years of professional experience to this shared resource. He provides training for wide-field and confocal microscopes and also supports sample preparation and training for SEM imaging.

The MSR is supported by our business administration associates Brittany Poast, Business Administrator and Alyssa High, Business Assistant. Support for MSR computer systems is provided by Andrew Hall, IT Systems Manager.

Contact Us

Microscopy Shared Resource
Biomedical Research Tower (BRT)
460 W. 12th Ave.
Columbus, OH 43210

Website: http://www.cmif.osu.edu

Lab Spaces: BRT, rooms 245, 264 and 268

Staff Offices: BRT, rooms 277 and 204

Phone: 614-292-9786

Email: cmif@osu.edu

Availability: Monday – Friday
Hours: 8 a.m. – 5 p.m.

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