The Microscopy Shared Resource (MSR) facilitates cancer research by providing an accessible centrally-organized resource with technical support for light and electron microscopy. Highly qualified faculty and staff provide training and advice for sample preparation, sample processing, basic microscopy and advanced training for imaging live samples. The MSR, a part of the larger Campus Microscopy and Imaging Facility (CMIF) under The Ohio State University Office of Research, is managed by the OSUCCC. The MSR is located within OSUCCC space in the Biomedical Research Tower. The ability to offer competitive pricing and exceptional service can be largely attributed to the generous support of outstanding institutional resources, including partnerships with the OSUCCC, the Office of Research and state and federal grants. The MSR gives researchers access to a full range of highly-specialized microscopes. MSR leadership and staff provide consultation and support for experimental design and implementation to support high-level cancer research with the latest microscopy techniques.
Paul Stoodley, PhD, director, is a professor of Microbial Infection and Immunity and Orthopaedics in the College of Medicine and has previous experience running imaging facilities for the Center for Genomic Sciences in Pittsburgh, PA, and at the NSF Center for Biofilm Engineering in Bozeman, MT. Dr. Stoodley has used confocal and electron microscopy extensively in his research and has developed a number of custom designed flow cell systems for live-cell imaging under physiological flow conditions. He has also developed methods for direct observation of clinical specimens and is co-inventor of patented methods for using reflected confocal microscopy to differentiate implant surfaces and matrix materials. These techniques will be developed in collaboration with the MSR team and our users to expand the capabilities of the MSR for use by OSUCCC researchers.
Sara Cole, PhD, associate director, received her PhD from the Department of Microbiology and Immunology at The Pennsylvania State University College of Medicine. She has over 20 years of experience in cancer research that has included the use of fluorescent and chromogenic labeling technologies and practical experience with wide-filed, confocal and live cell imaging techniques. Dr. Cole joined the MSR in 2010 and oversees the live-cell imaging and Multiphoton systems.
Sarah Mikula, BS, came to the CMIF with 15 years of histology experience, ten years of which has focused on electron microscopy sample preparation. She received her bachelor’s degree from the University of Oregon in Psychology. Ms. Mikula has experience with a broad range of TEM and SEM sample types with a focus on neural tissues in part, because of her keen interest in the mind and brain.
Brian Kemmenoe, BS, senior electron microscopist, received his bachelor’s degree in applied biology from North East London Polytechnic, England and brings nearly 30 years of professional experience to this shared resource. He provides training for wide-field and confocal microscopes and also supports sample preparation and training for SEM imaging.
The MSR is supported by our business administration associates Kris Fox, business administrator, and Tara Weld, business assistant. Support for MSR computer systems is provided by Andrew Hall, IT systems manager.