Services

The Microscopy Shared Resource (MSR) offers training tailored to the needs of the individual investigator on all microscope systems in the facility. Unique to the facility, consultation and support on subjects ranging from experimental design, troubleshooting and data analysis are also offered. Processing and analysis software for image presentation and publication is also available to Ohio State cancer researchers.

The MSR is the only facility on campus that provides processing of biological samples for evaluation using electron microscopy. These services include sample processing of TEM and SEM samples requiring different treatments in order to obtain optimal results. For SEM sample processing, the researcher can choose between chemical dehydration or critical point drying depending on the application and desired result. Traditional epoxy resin processing and sectioning are available for TEM sample observation. However, examination of soft materials such as biopolymers used as substrates for cell growth is very difficult to section using this approach. For optimal imaging of soft samples, a cryo-ultramicrotome is available to section these samples after freezing. Cryo-ultramicrotomy is also offered for observation of samples using light microscopy to assist in eliminating out of focus light, an issue that is often a result of autofluorescence. The MSR also offers negative staining as a means of observing samples when dehydration is not suitable for maintaining structure.

Fees

Listed prices are for The Ohio State University or federally-funded investigators. Please contact SR for external rates.

Instrument or Service

Rate

Basis

Transmission Electron Microscopy
Transmission Electron Microscope $20.00 1/2 Hour
Transmission Electron Microscopy Sample Preparation Service - Tissue $100.00 Per 3 Samples
Transmission Electron Microscopy Sample Preparation Service - Cell Monolayer $110.00/hour Per 3 Samples
Transmission Electron Microscopy Sample Preparation Service - Cell Pellet $120.00 Per 3 Samples
TEM Sample Sectioning Service $80.00 Per Sample
TEM Sample Sectioning Service (Thick sections only per block) $40.00 Per Sample
Scanning Electron Microscopy
Scanning Electron Microscope Coming Soon
Scanning Electron Microscopy Sample Preparation Service $90.00 Per 3 Samples
Critical Point Dryer $25.00 Hour
Sputter Coater $10.00 Hour
Cryo-Sample Preparation Service - High Pressure Freezing $75.00 Per 3 Samples
Confocal Microscopy
Confocal Laser Scanning Microscope (9-5) $30.00 Hour
Confocal Laser Scanning Microscope after-hours use $25.00 Hour
Multiphoton Microscopy
Multiphoton Confocal Laser Scanning Microscope $35.00 Hour
Multiphoton Confocal Laser Scanning Microscope $280.00 24 Hours
Live Cell Microscopy
Live Cell Confocal Laser Scanning Microscope $30.00 Hour
Live Cell Confocal Laser Scanning Microscope $240.00 24 Hours
Light Microscopy
Light Microscope - Widefield, Brightfield and Stereo $10.00 Hour
Spectral Camera (Nuance) $5.00 Hour
Sample Preparation Equipment
Ultramicrotome $10.00 Hour
Cryo-Ultramicrotome $30.00 Hour
Cryostat $10.00 Hour
Vibratome $10.00 Hour
Microwave Processing $5.00 Hour
Technical Assistance* $35.00 Hour
* Instrument training and requested user support during self-operation. All services include technical assistance charges.

Please enter a keyword (i.e. Name, Research Interest) or choose a Research Program

OR

Please enter a keyword (i.e. Name, Cancer Type) or choose a Principle Investigator

OR

Find a Scientific Publication