Ching-Shih Chen PhD

Ching-Shih Chen PhD
ProfessorCollege of Pharmacychen.844@osu.edu
336 Parks Hall 500 W 12th Avenue Columbus Ohio 43210
Phone:614-688-4008Fax: 614-688-8556
  • Molecular Carcinogenesis and Chemoprevention

Current Publications

  • Jiang Y, Wang J, Rozewski DM, Kolli S, Wu CH, Chen CS, Yang X, Hofmeister CC, Byrd JC, Johnson AJ, Phelps MASensitive liquid chromatography/mass spectrometry methods for quantification of pomalidomide in mouse plasma and brain tissue.J Pharm Biomed Anal in press 9/2/2013
  • Mao Y, Wang J, Zhao Y, Wu Y, Kwak KJ, Chen CS, Byrd JC, Lee RJ, Phelps MA, Lee LJ, Muthusamy NA novel liposomal formulation of FTY720 (Fingolimod) for promising enhanced targeted delivery.Nanomedicine in press 8/20/2013
  • Ma Y, McCarty SK, Kapuriya NP, Brendel VJ, Wang C, Zhang X, Jarjoura D, Saji M, Chen CS, Ringel MDDevelopment of p21 activated kinase-targeted multikinase inhibitors that inhibit thyroid cancer cell migration.J Clin Endocrinol Metab 98(8) E1314-22 8/1/2013
  • Bernot KM, Siebenaler RF, Whitman SP, Zorko NA, Marcucci GG, Santhanam R, Ahmed EH, Ngangana M, McConnell KK, Nemer JS, Brook DL, Kulp SK, Chen CS, Frankhouser D, Yan P, Bundschuh R, Zhang X, Dorrance AM, Dickerson K, Jarjoura D, Blum W, Marcucci G, Caligiuri MAToward personalized therapy in AML: in vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML.Leukemia in press 5/10/2013
  • Mims A, Walker AR, Huang X, Sun J, Wang H, Santhanam R, Dorrance AM, Walker C, Hoellerbauer P, Tarighat SS, Chan KK, Klisovic RB, Perrotti D, Caligiuri MA, Byrd JC, Chen CS, Lee LJ, Jacob S, Mrózek K, Bloomfield CD, Blum W, Garzon R, Schwind S, Marcucci GIncreased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia.Leukemia 27(4) 871-8 4/1/2013
  • Huang PH, Chuang HC, Chou CC, Wang H, Lee SL, Yang HC, Chiu HC, Kapuriya N, Wang D, Kulp SK, Chen CVitamin E facilitates the inactivation of the kinase Akt by the phosphatase PHLPP1.Sci Signal 6(267) ra19 3/19/2013
  • Berman-Booty L, Chu PC, Thomas-Ahner J, Bolon B, Wang D, Yang TS, Clinton SK, Kulp SK, Chen CSSuppression of prostate epithelial proliferation and intraprostatic progrowth signaling in transgenic mice by a new energy restriction-mimetic agent.Cancer Prev Res (Phila) 6(3) 232-41 3/1/2013
  • Burns SS, Akhmametyeva EM, Oblinger JL, Bush ML, Huang J, Senner V, Chen C, Jacob A, Welling DB, Chang LSHistone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth.Cancer Res 73(2) 792-803 1/15/2013
  • Lee SL, Chou CC, Chuang HC, Hsu EC, Chiu PC, Kulp SK, Byrd JC, Chen CSFunctional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.PLoS One 8(6) e67149 1/1/2013
  • Chu PC, Chuang HC, Kulp SK, Chen CThe mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition.J Biol Chem 287(52) 43639-50 12/21/2012
  • Booth L, Cruickshanks N, Ridder T, Chen C, Grant S, Dent POSU-03012 interacts with lapatinib to kill brain cancer cells.Cancer Biol Ther 13(14) 1501-11 12/1/2012
  • Lin HY, Kuo YC, Weng YI, Lai IL, Huang TH, Lin SP, Niu DM, Chen CActivation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent.Prostate 72(16) 1767-78 12/1/2012
  • Chuang HC, Kapuriya N, Kulp SK, Chen C, Shapiro CLDifferential anti-proliferative activities of poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer cells.Breast Cancer Res Treat 134(2) 649-59 7/1/2012
  • Lapalombella R, Yeh YY, Wang L, Ramanunni A, Rafiq S, Jha S, Staubli J, Lucas DM, Mani R, Herman SE, Johnson AJ, Lozanski A, Andritsos L, Jones J, Flynn JM, Lannutti B, Thompson P, Algate P, Stromatt S, Jarjoura D, Mo X, Wang D, Chen CS, Lozanski G, Heerema NA, Tridandapani S, Freitas MA, Muthusamy N, Byrd JCTetraspanin CD37 directly mediates transduction of survival and apoptotic signals.Cancer Cell 21(5) 694-708 5/15/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu