Richard Bruno, PhD, RDN
Leadership Title: Senior Director, Ohio State Second-Year Transformational Experience Program
Academic Title: Professor in the College of Food, Agricultural, and Environmental Sciences, College of Education and Human Ecology
Research Program: Molecular Carcinogenesis and Chemoprevention
About Me
More info forI am a a biomolecular nutritionist and registered dietitian with expertise in micronutrients, phytochemicals, functional foods, and advanced metabolism. I am the Carol S. Kennedy Professor of Human Nutrition in the Department of Human Sciences and Senior Director of Ohio State University’s Second-year Transformational Experience Program (STEP).
I lead the Diet & Cardiometabolic Health Lab, where research focuses on the bioavailability of phytochemicals and anti-inflammatory nutrition strategies to prevent cardiometabolic disorders, especially those implicated in hepatocellular carcinoma. My work also investigates how bioactive food components—such as polyphenols from green tea, vitamin E, vitamin C, and other phytochemicals—can reduce chronic inflammation and improve metabolic function
The goal of my translational research is to establish dietary strategies that support cardiometabolic health, providing practical approaches to mitigating the risks of obesity, (pre)diabetes, metabolic dysfunction-associated steatotic liver disease, and vascular endothelial dysfunction. My work combines human clinical trials and preclinical models to explore how dietary interventions can modulate oxidative stress, inflammation, and metabolic health along the gut-liver-blood vessel axis.
I am internationally recognized research have earned awards from the American Society of Nutrition and the OSU College of Education and Human Ecology. Since 2020, I have served as Editor-in-Chief of Nutrition Research and am on the editorial boards of several leading journals for the nutrition field. As Senior Director of STEP, I enhance the second-year student experience at Ohio State, focusing on faculty-student mentoring, student engagement, and curricular innovations that promote student retention, graduation and career-readiness.
Research Interests
More info for- Aberrant Crypt Foci
- Obesity
- Nutritional Sciences
- Microbiota
- Hyperglycemia
- Fatty Liver
- Mass Spectrometry
- Biochemistry
- Cardiovascular Diseases
- Inflammation
- Oxidative Stress
- Liver Diseases
Education & Training
More info forPost-doctoral
- Linus Pauling Institute - Oregon State University
Corvallis, OR
USA
Doctorate - PhD
- The Ohio State University
Columbus, OH
USA
Master's Degree - MS
- University of Delaware
Newark, DE
USA
Undergraduate Degree - BS
- University of Delaware
Newark, DE
USA
- Linus Pauling Institute - Oregon State University
Academic Office & Contact Information
More info forAcademic Office:
Evans Laboratory 3040
88 W 18th Ave
Columbus, Ohio 43210-1106Phone:
614-292-5522Email:
bruno.27@osu.eduPublications
More info forJune 7, 2024Spinal cord injury-induced metabolic impairment and steatohepatitis develops in non-obese rats and is exacerbated by premorbid obesity.
Goodus MT, Alfredo A, Carson KE, Dey P, Pukos N, Schwab JM, Popovich PG, Gao J, Mo X, Bruno RS, McTigue DM
Exp Neurol
February 5, 2024A green tea extract confection decreases circulating endotoxin and fasting glucose by improving gut barrier function but without affecting systemic inflammation: A double-blind, placebo-controlled randomized trial in healthy adults and adults with metabolic syndrome.
Zeng M, Hodges JK, Pokala A, Khalafi M, Sasaki GY, Pierson J, Cao S, Brock G, Yu Z, Zhu J, Vodovotz Y, Bruno RS
Nutr Res
June 28, 2022EGCG and Catechin Relative to Green Tea Extract Differentially Modulate the Gut Microbial Metabolome and Liver Metabolome To Prevent Obesity In Mice Fed A High-Fat Diet.
Sun X, Dey P, Bruno RS, Zhu J
J Nutr Biochem
November 28, 2020Catechin-Rich Green Tea Extract and the Loss-of-TLR4 Signaling Differentially Alter the Hepatic Metabolome in Mice with Nonalcoholic Steatohepatitis.
Sasaki GY, Li J, Cichon MJ, Kopec RE, Bruno RS
Mol Nutr Food Res