Cancer and Clinical Services Patient Stories

Dave Hill was “healthy as a horse,” so when he went to his doctor about what he thought may be a pinched nerve from working too hard at the gym, the last thing he expected was to leave with a diagnosis with stage III/IV follicular lymphoma.

“An MRI showed my lymph nodes were the size of softballs. When my doctor called, he said it was very likely I had cancer,” recalls Dave. 

He began extensive chemotherapy at his local hospital in July 2018. By January 2019, however, the disease had transformed into diffuse large B-cell lymphoma, which required a far different treatment approach. 

His doctor referred him to Kami Maddocks, MD, at the OSUCCC – James, where a subspecialized team of lymphoma experts did a robust work up of tests to determine the best course of action for his unique cancer. Dave underwent another six-month chemotherapy regimen in 2019. While the treatment was effective in hitting the pause button on his aggressive cancer growth, because his disease had transformed so quickly from follicular to diffuse large B-cell lymphoma, Maddocks recommended an autologous bone marrow transplant.

When cancer forms in the bone marrow, healthy stem cells — which serve as the basis of all healthy blood cells in the body — are crowded out by cancer cells. This leads to an increased risk of infection, blood clotting challenges and other issues. In order to treat this, cancer cells are destroyed with chemotherapy. Stem cells are removed from the patient and treated, and then patients receive very aggressive chemotherapy inpatient prior to the stem cells being infused back into the patient to generate healthy new blood cells.

“This was really hard to accept but, ultimately, I trust my team at the OSUCCC – James, so I took their advice and had the bone marrow transplant in September 2019,” says Dave.

Now 15 months into remission, he is happy to pay it forward to help support cancer research at the OSUCCC – James in any way he can. Most recently, that meant enrolling in a research study to determine how SARS-CoV-2 — commonly known as COVID-19 — impacts the immune system of cancer patients.

The study, led by Peter Shields, MD, deputy director of the OSUCCC – James, and Zihai Li, MD, PhD, director of the Pelotonia Institute for Immuno-Oncology, aims to advance the scientific community’s overall understanding of how effective the vaccine is for preventing COVID-19 infection, determine if the vaccine is less effective in cancer patients receiving certain therapies and learn how long the immunity lasts.

Dave says he is happy to give a few extra vials of blood and fill out some questionaries if it helps other people. “The James saved my life. Any time, in any way I can, I want to help,” he says. Dave, his wife Donna, and their son JD are actively involved in the Buckeye Cruise for Cancer, which has raised more than $25 million for cancer research at The James since its inception in 2008. 

Dave had just entered remission and was excited to begin living life freely again when the COVID-19 pandemic hit.

“Everybody is whining about being on house arrest during COVID, but I have been living this since June 2018. People living with cancer — especially those whose immune systems are temporarily wiped out from bone marrow transplant — are necessarily super hyper about infection precautions,” says Dave. “The pandemic just lengthened the necessity of extremely, cautious living. I’m so glad to finally have the opportunity to get the COVID vaccine. I encourage everyone else to do as soon as they qualify — for their protection and the protection of others.”

Ohio State patients who are currently in treatment or have been treated for cancer at the OSUCCC – James may qualify for the COVID-19 study. To learn more, visit cancer.osu.edu/SIIREN.