Jeffrey Parvin, MD, PhD
College of Medicine
Molecular Biology and Cancer Genetics
Breast Cancer, Cancer, DNA Damage, Ovarian Cancer, DNA Breaks, Double-Stranded
Jeffrey Parvin, MD, PhD, is a member of the Molecular Biology and Cancer Genetics Program at the OSUCCC – James, where his research focuses on biological processes in breast cancer.In particular, he investigates the pathways regulated by the BRCA1 tumor-suppressor proteins, as well as the processes involved in DNA damage repair, transcription of mRNA and epigenetics. Dr. Parvin has recently developed a high throughput technology for interpreting the functional effects of missense variants. One of his recent studies analyzed the DNA repair function of over 1,000 variants of the BRCA1 protein. Dr. Parvin has co-authored many articles in well-respected publications, including Nucleic Acids Research, Human Mutation, Genetics and Cancer Biology & Therapy.