Jonathan Song, PhD
College of Engineering
Mechanical & Aerospace Engineering
Molecular Biology and Cancer Genetics
Microfluidics, Physiopathology, Blood Vessels, Capillary Permeability, Extracellular Matrix
Dr. Song uses microscale engineering technology to reconstitute the microarchitecture of living tissue in vitro to systematically investigate how certain components of tumor microenvironment regulate angiogenesis. One of his research interests is understanding how the determinants of tumor blood flow such as elevated interstitial flow guide angiogenesis. Another research topic is dissecting the role of stromal fibroblasts in potentiating angiogenesis across multiple scales from secreted molecules, to multi-cellular morphogenesis, to tissue-matrix remodeling. Dr. Song is also interested in deploying these engineered microsystems for large-scale, high-throughput platforms for pre-clinical screening of multi-target anti-angiogenesis therapy.