Mary Dillhoff, MD

College

College of Medicine

Department/Division

Surgery

Academic Title

Asst Professor - Clinical

Research Program

Translational Therapeutics

Research Interest

Cancer, Pancreatic Cancer, Neuroendocrine Tumors, Neoplasm Metastasis, Pancreatitis, Chronic, DNA Damage, Neoplastic Processes

Dr. Dillhoff is a surgical oncologist with a research interest in upper gastrointestinal, hepatobiliary cancers and neuroendocrine tumors. She performs clinical research in these areas as well as basic science research with collaborators. Dr. Dillhoff is currently investigating circulating tumor DNA in patients with pancreatic cancer and cystic lesions of the pancreas. In neuroendocrine tumors we are evaluating adjuvant systemic therapies in metastatic pancreatic neuroendocrine tumors.

Education and Background

Office Location

N924 Doan Hall

410 W 10th Ave, Columbus, OH 43210

614-685-9824

Mary.Dillhoff@osumc.edu

Publications

Challenges of Surgical Management of Intrahepatic Cholangiocarcinoma.

Dillhoff M, Schmidt C, Pawlik TM, Cloyd JM, Squires MH

Expert Rev Gastroenterol Hepatol in press 06/18/2018
The Cost of Failure: Assessing the Cost-Effectiveness of Rescuing Patients from Major Complications After Liver Resection Using the National Inpatient Sample.

Merath K, Schmidt C, Chen Q, Dillhoff ME, Beal EW, Pawlik TM, Bagante F, Kimbrough CW, Cloyd JM, Idrees JJ, Rosinski BF, Ellison EC

J Gastrointest Surg in press 05/31/2018
Pre-operative Sarcopenia Identifies Patients at Risk for Poor Survival After Resection of Biliary Tract Cancers.

Dillhoff M, Galo J, Bagante F, Merath K, Sun SH, Cloyd J, Chakedis J, Pawlik TM, Spolverato G, Beal EW, Chafitz A, Woelfel I

J Gastrointest Surg in press 05/31/2018
Inflammatory myofibroblastic tumour: an unusual presentation including small bowel obstruction and palpable abdominal mass.

Dillhoff ME, Cerier E, Beal EW

BMJ Case Rep 2018 05/15/2018
Impact of Synchronous Liver Resection on the Perioperative Outcomes of Patients Undergoing CRS-HIPEC.

Dillhoff ME, Cloyd JM, Hays J, Pawlik TM, Schmidt C, Abdel-Misih S

J Gastrointest Surg in press 04/30/2018
Perioperative complications and the cost of rescue or failure to rescue in hepato-pancreato-biliary surgery.

Cloyd J, White S, Kimbrough CW, Merath K, Chen Q, Schmidt C, Bagante F, Beal EW, Pawlik TM, Dillhoff M

HPB (Oxford) in press 04/21/2018
Epidermoid cyst within an intrapancreatic accessory spleen.

Dillhoff ME, Beal EW, Paredes A

BMJ Case Rep 2018 04/05/2018
Impact of Post-Discharge Disposition on Risk and Causes of Readmission Following Liver and Pancreas Surgery.

White S, Cloyd J, Bagante F, Akgul O, Idrees JJ, Chen Q, Dillhoff M, Pawlik TM, Olsen G, Schmidt C, Beal EW, Merath K

J Gastrointest Surg in press 03/22/2018
Hospital Teaching Status and Medicare Expenditures for Hepato-Pancreato-Biliary Surgery.

Dillhoff M, White S, Merath K, Cloyd J, Beal EW, Bagante F, Diaz A, Idrees J, Chen Q, Pawlik TM, Schmidt C

World J Surg in press 03/21/2018
Sequential drain amylase to guide drain removal following pancreatectomy.

Zyromski NJ, McElhany AL, Schmidt C, Silberfein EJ, Dillhoff ME, Smith AC, Zhang Q, Villafane-Ferriol N, Massarweh NN, Fisher WE, Van Buren G 2nd, Tran Cao HS, Mendez-Reyes JE, Roch A, Hsu C, Oliva E

HPB (Oxford) in press 02/23/2018
Identification of patients at high risk for post-discharge venous thromboembolism after hepato-pancreato-biliary surgery: which patients benefit from extended thromboprophylaxis?

Schmidt CR, Abdel-Misih S, Chakedis J, Cloyd J, Zhang XF, Tumin D, Beal EW, Moris D, Porter E, Pawlik TM, Dillhoff M, Manilchuk A

HPB (Oxford) in press 02/19/2018
Exosomes in Pancreatic Cancer: from Early Detection to Treatment.

Moris D, Beal EW, Schmidt CR, Armstrong EA, Paredes AZ, Dillhoff ME, Pawlik TM, Chakedis J

J Gastrointest Surg in press 02/08/2018
Circulating monocyte chemoattractant protein-1 (MCP-1) is associated with cachexia in treatment-naïve pancreatic cancer patients.

Pawlik TM, Schmidt CR, Talbert EE, Sarna A, Lewis HL, Farren MR, Bloomston M, Guttridge DC, Haverick E, Rajasekera P, Dillhoff ME, Chakedis JM, Lesinski GB, Hart PA, Zimmers TA, Ramsey ML

J Cachexia Sarcopenia Muscle in press 01/07/2018
Perioperative cytokine levels portend early death after pancreatectomy for ductal adenocarcinoma.

Hart P, Rajasekera P, Guttridge D, Haverick E, Lewis HL, Dillhoff M, Bloomston M, Schmidt CR, Talbert E, Pawlik TM, Chakedis JM

J Surg Oncol in press 12/04/2017
Combination therapy with capecitabine and temozolomide in patients with low and high grade neuroendocrine tumors, with an exploratory analysis of O6-methylguanine DNA methyltransferase as a biomarker for response.

Schmidt CR, Sipos JA, Dillhoff ME, Owen DH, Konda B, Wei L, Abdel-Misih SRZ, Shah MH, Hemminger JA, Alexander AJ, Kirschner LS

Oncotarget 8 104046-104056 11/28/2017
Predictors of Pancreatic Cancer-Associated Weight Loss and Nutritional Interventions.

Nemer L, Krishna SG, Shah ZK, Conwell DL, Cruz-Monserrate Z, Dillhoff M, Guttridge DC, Hinton A, Manilchuk A, Pawlik TM, Schmidt CR, Talbert EE, Bekaii-Saab T, Hart PA

Pancreas 46 1152-1157 10/01/2017
Prognostic value of microRNA expression levels in pancreatic adenocarcinoma: a review of the literature.

Wald P, Liu XS, Pettit C, Dillhoff M, Manilchuk A, Schmidt C, Wuthrick E, Chen W, Williams TM

Oncotarget 8 73345-73361 09/22/2017
NF-?B regulates GDF-15 to suppress macrophage surveillance during early tumor development.

Ratnam NM, Peterson JM, Talbert EE, Ladner KJ, Rajasekera PV, Schmidt CR, Dillhoff ME, Swanson BJ, Haverick E, Kladney RD, Williams TM, Leone GW, Wang DJ, Guttridge DC

J Clin Invest in press 09/11/2017
Evaluating the American College of Surgeons National Surgical Quality Improvement project risk calculator: results from the U.S. Extrahepatic Biliary Malignancy Consortium.

Beal EW, Lyon E, Kearney J, Wei L, Ethun CG, Black SM, Dillhoff M, Salem A, Weber SM, Tran TB, Poultsides G, Shenoy R, Hatzaras I, Krasnick B, Fields RC, Buttner S, Scoggins CR, Martin RCG, Isom CA, Idrees K, Mogal HD, Shen P, Maithel SK, Pawlik TM, Schmidt CR

HPB (Oxford) in press 09/07/2017
Role of exosomes in treatment of hepatocellular carcinoma.

Moris D, Beal EW, Chakedis J, Burkhart RA, Schmidt C, Dillhoff M, Zhang X, Theocharis S, Pawlik TM

Surg Oncol 26 219-228 09/01/2017
Favorable and Durable Response to Pazopanib in Metastatic Refractory Paraganglioma.

Patel S, Owen D, Schmidt CR, Kirschner LS, Phay J, Shirley L, Dillhoff M, Brock P, Espinosa A, Shah MH, Konda B

J Oncol Pract in press 08/29/2017
Pancreatic Adenocarcinoma, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.

Tempero MA, Malafa MP, Al-Hawary M, Asbun H, Bain A, Behrman SW, Benson AB 3rd, Binder E, Cardin DB, Cha C, Chiorean EG, Chung V, Czito B, Dillhoff M, Dotan E, Ferrone CR, Hardacre J, Hawkins WG, Herman J, Ko AH, Komanduri S, Koong A, LoConte N, Lowy AM, Moravek C, Nakakura EK, O'Reilly EM, Obando J, Reddy S, Scaife C, Thayer S, Weekes CD, Wolff RA, Wolpin BM, Burns J, Darlow S

J Natl Compr Canc Netw 15 1028-1061 08/01/2017
Primary Pancreatic Secretinoma: Further Evidence Supporting Secretin as a Diarrheogenic Hormone.

Chey WY, Frankel WL, Roy S, Datta S, Sen CK, Dillhoff M, Muscarella P, Soergel KH, Tompkins RK, Chang TM, Bradley EL 3rd, Ellison EC

Ann Surg 266 346-352 08/01/2017
Association of Hospital Market Concentration With Costs of Complex Hepatopancreaticobiliary Surgery.

Cerullo M, Chen SY, Dillhoff M, Schmidt C, Canner JK, Pawlik TM

JAMA Surg in press e172158 07/26/2017
A Prospective Randomized Multicenter Trial of Distal Pancreatectomy With and Without Routine Intraperitoneal Drainage.

Van Buren G 2nd, Bloomston M, Schmidt CR, Behrman SW, Zyromski NJ, Ball CG, Morgan KA, Hughes SJ, Karanicolas PJ, Allendorf JD, Vollmer CM Jr, Ly Q, Brown KM, Velanovich V, Winter JM, McElhany AL, Muscarella P 2nd, Schmidt CM, House MG, Dixon E, Dillhoff ME, Trevino JG, Hallet J, Coburn NSG, Nakeeb A, Behrns KE, Sasson AR, Ceppa EP, Abdel-Misih SRZ, Riall TS, Silberfein EJ, Ellison EC, Adams DB, Hsu C, Tran Cao HS, Mohammed S, Villafañe-Ferriol N, Barakat O, Massarweh NN, Chai C, Mendez-Reyes JE, Fang A, Jo E, Mo Q, Fisher WE

Ann Surg in press 07/07/2017
Parenchymal-Sparing Versus Anatomic Liver Resection for Colorectal Liver Metastases: a Systematic Review.

Moris D, Ronnekleiv-Kelly S, Rahnemai-Azar AA, Felekouras E, Dillhoff M, Schmidt C, Pawlik TM

J Gastrointest Surg 21 1076-1085 06/01/2017
In vivo and ex vivo confocal endomicroscopy of pancreatic cystic lesions: A prospective study.

Krishna SG, Modi RM, Kamboj AK, Swanson BJ, Hart PA, Dillhoff ME, Manilchuk A, Schmidt CR, Conwell DL

World J Gastroenterol 23 3338-3348 05/14/2017
Intrahepatic cholangiocarcinoma: current management and emerging therapies.

Rahnemai-Azar AA, Weisbrod AB, Dillhoff M, Schmidt C, Pawlik TM

Expert Rev Gastroenterol Hepatol 11 439-449 05/01/2017
Current Management of Perihilar Cholangiocarcinoma and Future Perspectives.

Lewis HL, Rahnemai-Azar AA, Dillhoff M, Schmidt CR, Pawlik TM

Chirurgia (Bucur) 112 193-207 05/01/2017
Needle-based confocal laser endomicroscopy for the diagnosis of pancreatic cystic lesions: an international external interobserver and intraobserver study (with videos).

Krishna SG, Brugge WR, Dewitt JM, Kongkam P, Napoleon B, Robles-Medranda C, Tan D, El-Dika S, McCarthy S, Walker J, Dillhoff ME, Manilchuk A, Schmidt C, Swanson B, Shah ZK, Hart PA, Conwell DL

Gastrointest Endosc in press 03/10/2017
Pancreatic neuroendocrine microadenomatosis: A case report of cytology and histology correlation.

Vo N, Cohen DW, Dillhoff ME, Jin M

Diagn Cytopathol 45 143-147 02/01/2017
Cystic pancreatic neuroendocrine tumors: correlation of in vivo needle-based confocal endomicroscopic findings by ex vivo analysis.

Kamboj AK, Swanson B, Dillhoff ME, Conwell DL, Krishna SG

Gastrointest Endosc 85 259-260 01/01/2017
Pancreaticoduodenectomy outcomes in the pediatric, adolescent, and young adult population.

Mansfield SA, Mahida JB, Dillhoff M, Porter K, Conwell D, Ranalli M, Walker JP, Aldrink JH

J Surg Res 204 232-6 07/01/2016
Elevated Alkaline Phosphatase Prior to Transarterial Chemoembolization for Neuroendocrine Tumors Predicts Worse Outcomes.

Onesti JK, Shirley LA, Saunders ND, Davidson GW, Dillhoff ME, Khabiri H, Guy GE, Dowell JD, Schmidt CR, Shah MH, Bloomston M

J Gastrointest Surg 20 580-6 03/01/2016
Pretransplant Locoregional Therapy for Hepatocellular Carcinoma: Evaluation of Explant Pathology and Overall Survival.

Beal EW, Dittmar KM, Hanje AJ, Michaels AJ, Conteh L, Davidson G, Black SM, Bloomston PM, Dillhoff ME, Schmidt CR

Front Oncol 6 143 01/01/2016
Appendiceal Mixed Adeno-Neuroendocrine Carcinoma: A Population-Based Study of the Surveillance, Epidemiology, and End Results Registry.

Brathwaite S, Yearsley MM, Bekaii-Saab T, Wei L, Schmidt CR, Dillhoff ME, Frankel WL, Hays JL, Wu C, Abdel-Misih S

Front Oncol 6 148 01/01/2016