Mary Dillhoff, MD

College

College of Medicine

Department/Division

Surgery

Academic Title

Asst Professor - Clinical

Research Program

Translational Therapeutics

Research Interest

Cancer ● Pancreatic Cancer ● Neuroendocrine Tumors ● Neoplasm Metastasis ● Pancreatitis, Chronic ● DNA Damage ● Neoplastic Processes

Dr. Dillhoff is a surgical oncologist with a research interest in upper gastrointestinal, hepatobiliary cancers and neuroendocrine tumors. She performs clinical research in these areas as well as basic science research with collaborators. Dr. Dillhoff is currently investigating circulating tumor DNA in patients with pancreatic cancer and cystic lesions of the pancreas. In neuroendocrine tumors we are evaluating adjuvant systemic therapies in metastatic pancreatic neuroendocrine tumors.

Education

Doctorate, University of Cincinnati College of Medicine

Cincinnati, OH (USA)
Doctorate, University of Cincinnati College of Medicine

Cincinnati, OH (USA)

Residencies

The Ohio State University Medical Center

Columbus, OH (USA)

Office Location

N924 Doan Hall

410 W 10th Ave, Columbus, OH 43210

614-685-9824

Mary.Dillhoff@osumc.edu

Publications

Population-Based Assessment of Selective Drain Placement During Pancreatoduodenectomy Using the Modified Fistula Risk Score.

Xourafas D, Ejaz A, Tsung A, Dillhoff M, Pawlik TM, Cloyd JM

J Am Coll Surg 228 583-591 04/01/2019
Predictive Value of Chromogranin A and a Pre-Operative Risk Score to Predict Recurrence After Resection of Pancreatic Neuroendocrine Tumors.

Fisher AV, Lopez-Aguiar AG, Rendell VR, Pokrzywa C, Rocha FG, Kanji ZS, Poultsides GA, Makris EA, Dillhoff ME, Beal EW, Fields RC, Panni RZ, Idrees K, Smith PM, Cho CS, Beems MV, Maithel SK, Winslow ER, Abbott DE, Weber SM

J Gastrointest Surg 23 651-658 04/01/2019
Routine intensive care unit admission among patients undergoing major pancreatic surgery for cancer: No effect on failure to rescue.

Cerullo M, Gani F, Chen SY, Canner JK, Dillhoff M, Cloyd J, Pawlik TM

Surgery 165 741-746 04/01/2019
Validation of early drain removal after pancreatoduodenectomy based on modified fistula risk score stratification: a population-based assessment.

Xourafas D, Ejaz A, Tsung A, Dillhoff M, Pawlik TM, Cloyd JM

HPB (Oxford) in press 03/18/2019
Procedure-Specific Volume and Nurse-to-Patient Ratio: Implications for Failure to Rescue Patients Following Liver Surgery.

Chen Q, Olsen G, Bagante F, Merath K, Idrees JJ, Akgul O, Cloyd J, Dillhoff M, White S, Pawlik TM

World J Surg 43 910-919 03/01/2019
Influence of carcinoid syndrome on the clinical characteristics and outcomes of patients with gastroenteropancreatic neuroendocrine tumors undergoing operative resection.

Kimbrough CW, Beal EW, Dillhoff ME, Schmidt CR, Pawlik TM, Lopez-Aguiar AG, Poultsides G, Makris E, Rocha FG, Crown A, Abbott DE, Fisher AV, Fields RC, Krasnick BA, Idrees K, Marincola-Smith P, Cho CS, Beems M, Maithel SK, Cloyd JM

Surgery 165 657-663 03/01/2019
Association Between Travel Distance, Hospital Volume, and Outcomes Following Resection of Cholangiocarcinoma.

Beal EW, Mehta R, Hyer JM, Paredes A, Merath K, Dillhoff ME, Cloyd J, Ejaz A, Pawlik TM

J Gastrointest Surg in press 02/27/2019
Use of perioperative epidural analgesia among Medicare patients undergoing hepatic and pancreatic surgery.

Merath K, Hyer JM, Mehta R, Bagante F, Paredes A, Wu L, Sahara K, Dillhoff M, Cloyd J, Ejaz A, Tsung A, Pawlik TM

HPB (Oxford) in press 02/02/2019
The impact of failure to achieve symptom control after resection of functional neuroendocrine tumors: An 8-institution study from the US Neuroendocrine Tumor Study Group.

Zaidi MY, Lopez-Aguiar AG, Poultsides GA, Dillhoff M, Rocha FG, Idrees K, Nathan H, Winslow ER, Fields RC, Cardona K, Maithel SK, and other members of the US Neuroendocrine Tumor Study Group

J Surg Oncol 119 5-11 01/01/2019
Gastric carcinoids: Does type of surgery or tumor affect survival?

Crown A, Kennecke H, Kozarek R, Lopez-Aguiar AG, Dillhoff M, Beal EW, Poultsides GA, Makris E, Idrees K, Smith PM, Nathan H, Beems M, Abbott D, Fisher AV, Fields RC, Davidson J, Maithel SK, Rocha FG

Am J Surg in press 12/28/2018
Neutrophil Lymphocyte Ratio and Transarterial Chemoembolization in Neuroendocrine Tumor Metastases.

McDermott SM, Saunders ND, Schneider EB, Strosberg D, Onesti J, Dillhoff M, Schmidt CR, Shirley LA

J Surg Res 232 369-375 12/01/2018
Implementation and early outcomes for a surgeon-directed hepatic arterial infusion pump program for colorectal liver metastases.

Chakedis J, Beal EW, Sun S, Galo J, Chafitz A, Davidson G, Reardon J, Dillhoff M, Pawlik TM, Abdel-Misih S, Bloomston M, Schmidt CR

J Surg Oncol 118 1065-1073 12/01/2018
Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy-Stratification of Patient Risk.

Akgul O, Merath K, Mehta R, Hyer JM, Chakedis J, Wiemann B, Johnson M, Paredes A, Dillhoff M, Cloyd J, Pawlik TM

J Gastrointest Surg in press 11/26/2018
Prognostic Role of Lymph Node Positivity and Number of Lymph Nodes Needed for Accurately Staging Small Bowel Neuroendocrine Tumors.

Zaidi MY, Lopez-Aguiar AG, Dillhoff M, Beal E, Poultsides G, Makris E, Rocha F, Crown A, Idrees K, Marincola Smith P, Nathan H, Beems M, Abbott D, Barrett JR, Fields RC, Davidson J, Cardona K, Maithel SK

JAMA Surg in press 10/31/2018
Pre-operative Sarcopenia Identifies Patients at Risk for Poor Survival After Resection of Biliary Tract Cancers.

Chakedis J, Spolverato G, Beal EW, Woelfel I, Bagante F, Merath K, Sun SH, Chafitz A, Galo J, Dillhoff M, Cloyd J, Pawlik TM

J Gastrointest Surg 22 1697-1708 10/01/2018
The Cost of Failure: Assessing the Cost-Effectiveness of Rescuing Patients from Major Complications After Liver Resection Using the National Inpatient Sample.

Idrees JJ, Kimbrough CW, Rosinski BF, Schmidt C, Dillhoff ME, Beal EW, Bagante F, Merath K, Chen Q, Cloyd JM, Ellison EC, Pawlik TM

J Gastrointest Surg 22 1688-1696 10/01/2018
Impact of Synchronous Liver Resection on the Perioperative Outcomes of Patients Undergoing CRS-HIPEC.

Cloyd JM, Abdel-Misih S, Hays J, Dillhoff ME, Pawlik TM, Schmidt C

J Gastrointest Surg 22 1576-1584 09/01/2018
Perioperative complications and the cost of rescue or failure to rescue in hepato-pancreato-biliary surgery.

Chen Q, Beal EW, Kimbrough CW, Bagante F, Merath K, Dillhoff M, Schmidt C, White S, Cloyd J, Pawlik TM

HPB (Oxford) 20 854-864 09/01/2018
Challenges of surgical management of intrahepatic cholangiocarcinoma.

Squires MH, Cloyd JM, Dillhoff M, Schmidt C, Pawlik TM

Expert Rev Gastroenterol Hepatol 12 671-681 07/01/2018
Impact of Post-Discharge Disposition on Risk and Causes of Readmission Following Liver and Pancreas Surgery.

Chen Q, Merath K, Olsen G, Bagante F, Idrees JJ, Akgul O, Cloyd J, Schmidt C, Dillhoff M, Beal EW, White S, Pawlik TM

J Gastrointest Surg 22 1221-1229 07/01/2018
Inflammatory myofibroblastic tumour: an unusual presentation including small bowel obstruction and palpable abdominal mass.

Cerier E, Beal EW, Dillhoff ME

BMJ Case Rep 2018 05/15/2018
Perioperative cytokine levels portend early death after pancreatectomy for ductal adenocarcinoma.

Lewis HL, Chakedis JM, Talbert E, Haverick E, Rajasekera P, Hart P, Bloomston M, Dillhoff M, Pawlik TM, Guttridge D, Schmidt CR

J Surg Oncol 117 1260-1266 05/01/2018
Epidermoid cyst within an intrapancreatic accessory spleen.

Paredes A, Beal EW, Dillhoff ME

BMJ Case Rep 2018 04/05/2018
Role of associating liver partition and portal vein ligation in staged hepatectomy (ALPPS)-strategy for colorectal liver metastases.

Abbasi A, Rahnemai-Azar AA, Merath K, Weber SM, Abbott DE, Dillhoff M, Cloyd J, Pawlik TM

Transl Gastroenterol Hepatol 3 66 01/01/2018
Hospital Teaching Status and Medicare Expenditures for Hepato-Pancreato-Biliary Surgery.

Chen Q, Bagante F, Merath K, Idrees J, Beal EW, Cloyd J, Dillhoff M, Schmidt C, Diaz A, White S, Pawlik TM

World J Surg 42 2969-2979 01/01/2018
Exosomes in Pancreatic Cancer: from Early Detection to Treatment.

Armstrong EA, Beal EW, Chakedis J, Paredes AZ, Moris D, Pawlik TM, Schmidt CR, Dillhoff ME

J Gastrointest Surg 22 737-750 01/01/2018
Identification of patients at high risk for post-discharge venous thromboembolism after hepato-pancreato-biliary surgery: which patients benefit from extended thromboprophylaxis?

Beal EW, Tumin D, Chakedis J, Porter E, Moris D, Zhang XF, Abdel-Misih S, Dillhoff M, Manilchuk A, Cloyd J, Schmidt CR, Pawlik TM

HPB (Oxford) 20 621-630 01/01/2018
Sequential drain amylase to guide drain removal following pancreatectomy.

Villafane-Ferriol N, Van Buren G 2nd, Mendez-Reyes JE, McElhany AL, Massarweh NN, Silberfein EJ, Hsu C, Tran Cao HS, Schmidt C, Zyromski NJ, Dillhoff ME, Roch A, Oliva E, Smith AC, Zhang Q, Fisher WE

HPB (Oxford) 20 514-520 01/01/2018
Circulating monocyte chemoattractant protein-1 (MCP-1) is associated with cachexia in treatment-naïve pancreatic cancer patients.

Talbert EE, Lewis HL, Farren MR, Ramsey ML, Chakedis JM, Rajasekera P, Haverick E, Sarna A, Bloomston M, Pawlik TM, Zimmers TA, Lesinski GB, Hart PA, Dillhoff ME, Schmidt CR, Guttridge DC

J Cachexia Sarcopenia Muscle 9 358-368 01/01/2018
Combination therapy with capecitabine and temozolomide in patients with low and high grade neuroendocrine tumors, with an exploratory analysis of O6-methylguanine DNA methyltransferase as a biomarker for response.

Owen DH, Alexander AJ, Konda B, Wei L, Hemminger JA, Schmidt CR, Abdel-Misih SRZ, Dillhoff ME, Sipos JA, Kirschner LS, Shah MH

Oncotarget 8 104046-104056 11/28/2017
NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development.

Ratnam NM, Peterson JM, Talbert EE, Ladner KJ, Rajasekera PV, Schmidt CR, Dillhoff ME, Swanson BJ, Haverick E, Kladney RD, Williams TM, Leone GW, Wang DJ, Guttridge DC

J Clin Invest 127 3796-3809 10/02/2017
Needle-based confocal laser endomicroscopy for the diagnosis of pancreatic cystic lesions: an international external interobserver and intraobserver study (with videos).

Krishna SG, Brugge WR, Dewitt JM, Kongkam P, Napoleon B, Robles-Medranda C, Tan D, El-Dika S, McCarthy S, Walker J, Dillhoff ME, Manilchuk A, Schmidt C, Swanson B, Shah ZK, Hart PA, Conwell DL

Gastrointest Endosc 86 644-654.e2 10/01/2017
Prognostic value of microRNA expression levels in pancreatic adenocarcinoma: a review of the literature.

Wald P, Liu XS, Pettit C, Dillhoff M, Manilchuk A, Schmidt C, Wuthrick E, Chen W, Williams TM

Oncotarget 8 73345-73361 09/22/2017
Association of Hospital Market Concentration With Costs of Complex Hepatopancreaticobiliary Surgery.

Cerullo M, Chen SY, Dillhoff M, Schmidt C, Canner JK, Pawlik TM

JAMA Surg 152 e172158 09/20/2017
Role of exosomes in treatment of hepatocellular carcinoma.

Moris D, Beal EW, Chakedis J, Burkhart RA, Schmidt C, Dillhoff M, Zhang X, Theocharis S, Pawlik TM

Surg Oncol 26 219-228 09/01/2017
In vivo and ex vivo confocal endomicroscopy of pancreatic cystic lesions: A prospective study.

Krishna SG, Modi RM, Kamboj AK, Swanson BJ, Hart PA, Dillhoff ME, Manilchuk A, Schmidt CR, Conwell DL

World J Gastroenterol 23 3338-3348 05/14/2017
Intrahepatic cholangiocarcinoma: current management and emerging therapies.

Rahnemai-Azar AA, Weisbrod AB, Dillhoff M, Schmidt C, Pawlik TM

Expert Rev Gastroenterol Hepatol 11 439-449 05/01/2017
Current Management of Perihilar Cholangiocarcinoma and Future Perspectives.

Lewis HL, Rahnemai-Azar AA, Dillhoff M, Schmidt CR, Pawlik TM

Chirurgia (Bucur) 112 193-207 05/01/2017
Pancreatic neuroendocrine microadenomatosis: A case report of cytology and histology correlation.

Vo N, Cohen DW, Dillhoff ME, Jin M

Diagn Cytopathol 45 143-147 02/01/2017
Parenchymal-Sparing Versus Anatomic Liver Resection for Colorectal Liver Metastases: a Systematic Review.

Moris D, Ronnekleiv-Kelly S, Rahnemai-Azar AA, Felekouras E, Dillhoff M, Schmidt C, Pawlik TM

J Gastrointest Surg 21 1076-1085 01/01/2017
A Prospective Randomized Multicenter Trial of Distal Pancreatectomy With and Without Routine Intraperitoneal Drainage.

Van Buren G 2nd, Bloomston M, Schmidt CR, Behrman SW, Zyromski NJ, Ball CG, Morgan KA, Hughes SJ, Karanicolas PJ, Allendorf JD, Vollmer CM Jr, Ly Q, Brown KM, Velanovich V, Winter JM, McElhany AL, Muscarella P 2nd, Schmidt CM, House MG, Dixon E, Dillhoff ME, Trevino JG, Hallet J, Coburn NSG, Nakeeb A, Behrns KE, Sasson AR, Ceppa EP, Abdel-Misih SRZ, Riall TS, Silberfein EJ, Ellison EC, Adams DB, Hsu C, Tran Cao HS, Mohammed S, Villafañe-Ferriol N, Barakat O, Massarweh NN, Chai C, Mendez-Reyes JE, Fang A, Jo E, Mo Q, Fisher WE

Ann Surg 266 421-431 01/01/2017
Predictors of Pancreatic Cancer-Associated Weight Loss and Nutritional Interventions.

Nemer L, Krishna SG, Shah ZK, Conwell DL, Cruz-Monserrate Z, Dillhoff M, Guttridge DC, Hinton A, Manilchuk A, Pawlik TM, Schmidt CR, Talbert EE, Bekaii-Saab T, Hart PA

Pancreas 46 1152-1157 01/01/2017
Evaluating the American College of Surgeons National Surgical Quality Improvement project risk calculator: results from the U.S. Extrahepatic Biliary Malignancy Consortium.

Beal EW, Lyon E, Kearney J, Wei L, Ethun CG, Black SM, Dillhoff M, Salem A, Weber SM, Tran TB, Poultsides G, Shenoy R, Hatzaras I, Krasnick B, Fields RC, Buttner S, Scoggins CR, Martin RCG, Isom CA, Idrees K, Mogal HD, Shen P, Maithel SK, Pawlik TM, Schmidt CR

HPB (Oxford) 19 1104-1111 01/01/2017
Favorable and Durable Response to Pazopanib in Metastatic Refractory Paraganglioma.

Patel S, Owen D, Schmidt CR, Kirschner LS, Phay J, Shirley L, Dillhoff M, Brock P, Espinosa A, Shah MH, Konda B

J Oncol Pract 13 840-842 01/01/2017
Pancreatic Adenocarcinoma, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.

Tempero MA, Malafa MP, Al-Hawary M, Asbun H, Bain A, Behrman SW, Benson AB 3rd, Binder E, Cardin DB, Cha C, Chiorean EG, Chung V, Czito B, Dillhoff M, Dotan E, Ferrone CR, Hardacre J, Hawkins WG, Herman J, Ko AH, Komanduri S, Koong A, LoConte N, Lowy AM, Moravek C, Nakakura EK, O'Reilly EM, Obando J, Reddy S, Scaife C, Thayer S, Weekes CD, Wolff RA, Wolpin BM, Burns J, Darlow S

J Natl Compr Canc Netw 15 1028-1061 01/01/2017
Cystic pancreatic neuroendocrine tumors: correlation of in vivo needle-based confocal endomicroscopic findings by ex vivo analysis.

Kamboj AK, Swanson B, Dillhoff ME, Conwell DL, Krishna SG

Gastrointest Endosc 85 259-260 01/01/2017
Primary Pancreatic Secretinoma: Further Evidence Supporting Secretin as a Diarrheogenic Hormone.

Chey WY, Frankel WL, Roy S, Datta S, Sen CK, Dillhoff M, Muscarella P, Soergel KH, Tompkins RK, Chang TM, Bradley EL 3rd, Ellison EC

Ann Surg 266 346-352 01/01/2017
Elevated Alkaline Phosphatase Prior to Transarterial Chemoembolization for Neuroendocrine Tumors Predicts Worse Outcomes.

Onesti JK, Shirley LA, Saunders ND, Davidson GW, Dillhoff ME, Khabiri H, Guy GE, Dowell JD, Schmidt CR, Shah MH, Bloomston M

J Gastrointest Surg 20 580-6 03/01/2016
Pancreaticoduodenectomy outcomes in the pediatric, adolescent, and young adult population.

Mansfield SA, Mahida JB, Dillhoff M, Porter K, Conwell D, Ranalli M, Walker JP, Aldrink JH

J Surg Res 204 232-6 01/01/2016
Pretransplant Locoregional Therapy for Hepatocellular Carcinoma: Evaluation of Explant Pathology and Overall Survival.

Beal EW, Dittmar KM, Hanje AJ, Michaels AJ, Conteh L, Davidson G, Black SM, Bloomston PM, Dillhoff ME, Schmidt CR

Front Oncol 6 143 01/01/2016
Appendiceal Mixed Adeno-Neuroendocrine Carcinoma: A Population-Based Study of the Surveillance, Epidemiology, and End Results Registry.

Brathwaite S, Yearsley MM, Bekaii-Saab T, Wei L, Schmidt CR, Dillhoff ME, Frankel WL, Hays JL, Wu C, Abdel-Misih S

Front Oncol 6 148 01/01/2016