Patrick L Green, PhD
College of Veterinary Medicine
Brain Injuries, Subarachnoid Hemorrhage, Edema, Hypertension, Wounds and Injuries, Brain Ischemia
Patrick Green, PhD, is a professor and associate dean for research and graduate studies in the College of Veterinary Medicine at Ohio State, where he also directs the Center for Retrovirus Research and is a member of the OSUCCC – James Leukemia Research Program.Dr. Green’s research focuses on understanding the molecular basis of T-lymphocyte transformation, as well as the induction of leukemia/lymphoma and neurological diseases by the human T-cell leukemia viruses (HTLVs). He investigates viral and cellular regulators of HTLV gene expression/replication, cellular transformation and virus survival or persistence in infected hosts. Recent work has revealed the importance of a viral gene, termed Hbz, in the maintenance and proliferation of HTLV-1 infected cells. In fact, Hbz is the only viral gene consistently expressed in HTLV-1 associated adult T cell leukemia/lymphoma. Hbz and the cellular pathways it impacts will be important targets for treatment and prevention of HTLV-1-associated diseases. Dr. Green has authored or co-authored many articles in well-regarded publications, including Viruses, Journal of Virology, Journal of Biological Chemistry and Cancer Science.