Peixuan Guo, PhD
College of Pharmacy
Dr. Guo’s major research interest is to apply RNA nanotechnology for cancer therapy. His lab has developed multifunctional RNA nanoparticles harboring RNA aptamer, siRNA, anti-miRNA, drugs or ribozymes. RNA nanoparticles are envisioned to be a major breakthrough in cancer therapy as they are homogeneous in size and structure; thermodynamically and chemically stable; non-toxic; non-immunogenic; and display favorable pharmacological profiles. After systemic injection, the RNA nanoparticles specifically targeted tumors with little or no accumulation in healthy organs. Ongoing projects include development of RNA nanoparticles for tumor specific delivery of therapeutics, image-guided drug delivery, and cancer immunotherapy.