A Microbiome Metabolism & Cancer Epigenetics Lab
The Zheng Lab at the OSUCCC – James, led by internationally recognized cancer research specialist and principal investigator Qingfei Zheng, PhD, aims to understand the mechanisms of cancer-related metabolic disorders and epigenetic dysregulation.
Inspired by a goal to develop new cancer therapeutics at the atomic level, the world-renowned specialists and subspecialists in Dr. Zheng’s Microbiome Metabolism & Cancer Epigenetics Lab strive to apply chemical and synthetic biology approaches to study cancer metabolism, epigenetics and tumor microbiome.
Mission
At the OSUCCC – James, the Zheng Lab’s mission is to apply multidisciplinary technologies to study tumor microenvironment, microbiome metabolism and epigenetics in order to develop new personalized cancer therapeutics.
There is no routine cancer, and through chemical and synthetic biology approaches, the specialists and subspecialists in Dr. Zheng’s Microbiome Metabolism & Cancer Epigenetics Lab strive to create individualized therapies to fight cancer based on each patient’s individual biological makeup.
How We Do It
Dr. Zheng’s Microbiome Metabolism & Cancer Epigenetics Lab comprises world-renowned research experts working collaboratively to understand the mechanisms of cancer-related metabolic disorders and epigenetic dysregulation in an effort to better develop new, individualized cancer therapeutics.
The specialists and subspecialists in the Zheng Lab believe that all cancers and cancer-related diseases are attributed to abnormal biochemical processes. By interfering with these processes and utilizing chemical and synthetic biology strategies – as well as by understanding how tumor microbiome metabolism contributes to carcinogenesis (e.g., blocking host-microbe interaction pathways and the “Trojan Horse” bacterial therapy strategies utilizing engineered intratumoral bacteria) – these researchers can facilitate developing new, personalized, anticancer therapies.