Craig J Burd, PhD
College of Arts & Sciences
Molecular Carcinogenesis and Chemoprevention
Prostatic Cancer ● Adenocarcinoma ● Cancer, Hormone-Dependent ● Cancer ● Breast Cancer ● Autoimmunity ● Mammary Cancer, Experimental ● Endometrial Cancer ● Neovascularization, Pathologic ● Sequence Deletion
Craig Burd, PhD, is a member of the Molecular Carcinogenesis and Chemoprevention Program at the OSUCCC – James. His work explores the molecular mechanisms controlling estrogen signaling and how, when not properly maintained, these mechanisms may influence breast cancer risk and therapeutic relapse.Of particular interest to his team is the potential of environmental chemicals (known as endocrine disruptors) to influence breast cancer risk. These endocrine disruptors, which everyone is exposed to daily, have the ability to mimic estrogen and thus influence cancer susceptibility. Dr. Burd and his team recently identified a window during the first trimester of embryonic development that is particularly susceptible to these compounds. The researchers believe that exposure during this period increases a woman’s risk of getting breast cancer in adulthood. The goal of this research is to define the mechanisms by which these compounds may permanently increase the risk of cancer and to identify biomarkers in the human population that can help determine if certain industrial compounds are harming the next generation of women who are now being exposed during fetal development.