“Precision cancer medicine” refers to a new standard of cancer care based on genomics that is making its way into the clinic. The word “precision" refers to the use of genomic technologies that provide additional information to aid cancer diagnosis and treatment. Precision cancer medicine is already having a profound influence on clinical cancer care and clinical trial design, and it likely will move us away from the current organ based classification of cancer to a molecular-based taxonomy.
Research conducted by the Roychowdhury Laboratory Team includes basic cancer research and translational cancer genomics.
We are a multidisciplinary group with team members who have expertise in diverse fields including cancer genomics, computational biology/computer science, cancer biology, drug development, molecular diagnostics and medical oncology.
Basic cancer research is about the core principles of cancer, while translational cancer research is about using this knowledge to take care of patients through clinical trials. Together, as a multidisciplinary team, we:
- Evaluate and care for patients through clinical trials
- Study the genetics of cancer using next generation sequencing
- Match patients to new smart drugs in trials
- Evaluate the benefit from such therapies
- Study how drugs affect the cancer
- Strive to develop rational combination treatments for patients
We are grateful to the Government and Foundation efforts that strive to end cancer and work tirelessly to fund much needed cancer research. The following are agencies that have supported our team directly:
- Prostate Cancer Foundation, Young Investigator Award
- Prostate Cancer Foundation, Special Creativity Award
- American Cancer Society, Mentored Research Scholar Grant
- Fore Cancer Research Foundation
- Pelotonia Idea Grant
- National Cancer Institute, Experimental Therapeutic Network UM1
- National Human Genome Research Institute
There are many questions and problems that we must solve for cancer research, and there are very few resources available to fund cancer research. While funding from National Institutes of Health and foundations can fund a fraction of research, we rely on philanthropic donations to further cancer research.
Donations are especially important since the National Institutes of Health and Foundations are less likely to fund high risk ideas which have the greatest potential to change how we approach cancer.
Join our Team
To accomplish our mission, we promote an environment for teamwork and training for all team members at every stage of training.
We are actively recruiting team members, including graduate students, post-doctoral trainees, and clinical fellows for projects in the following areas:
- Cancer Genomics
- Target Discovery
- Novel NGS assay development
- Acquired resistance to novel kinase inhibitors, including FGFR pathway and others
- Evaluation of exceptional responders
- Computational biology for cancer molecular diagnostics and acquired drug resistance
For applicants with considerable computer science experience, we also offer a specialized translational cancer genomics: computational biology internship (candidates should inquire).
Interested applicants should contact us at Sameek.Roychowdhury@osumc.edu and include the following:
- Area of research interest in our lab
- Cover letter indicating current and future research interests and expected availability date
- CV (Curriculum Vitae) or biosketch, with names of three references