James researchers have found a way to use genomics – the study and analysis of DNA in tumor cells – to significantly improve radiation treatment. Radiation oncology expert Dr. Terence Williams explains how a recent study found that certain cell mutations may cause resistance to radiation treatment. The research focused on a protein called K-RAS, which frequently mutates in a number of different cancers (including colorectal, pancreas, lung and ovarian cancers) and causes this radiation resistance. By understanding how this protein works, James experts now have specific molecular targets on which to focus, and can develop better, more personalized therapies for each patient and their unique cancers.